- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00688285
Automated Clinical Reminders in the Care of Chronic Kidney Disease Patients (ACRinCKD)
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Literature supports that most chronic kidney disease (CKD) patients are cared for by primary care physicians (PCP) without the help of a kidney specialist. Many of these patients fail to achieve targeted outcomes and late referral to a nephrologist has been associated with an increased risk of death. Automated computerized clinical reminders have been shown to improve physician compliance with recommended guidelines in other settings.
Aims: To determine if clinical reminders can help PCPs decrease the rate of late referrals, improve urine albumin checks in CKD patients
Design: prospective randomized controlled, single-blinded study with additional historical control
Methods: Two 20-minute teaching sessions aimed at all GIM PCPs in the UPMC clinic followed by randomization of the eligible GIM providers to receive automated clinical reminders (CR) for their CKD stage 3b-5 patients versus routine care.
Outcomes: Using a database search, individuals with an eGFR<45ml/min/1.73m2 (not seen by a nephrologist) will have data collected on: PCP referral to a nephrologist, urinary albumin (or protein) quantification in the past year, PCP recognition of patients with eGFR<45ml/min, ACE/ARB usage.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
Pennsylvania
-
Pittsburgh, Pennsylvania, United States, 15261
- University of Pittsburgh
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- For PCPs: all GIM attending physicians with a weekly continuity clinic.
- For patients: >= 18 years-old with an eGFR<45ml/min/1.73m2 being seen in the UPMC GIM clinic by a faculty member during the 10-month intervention period
Exclusion Criteria:
- for PCPs: imminent plans to leave the department
- patients with a renal transplant, on any form of dialysis, or with a previous nephrology evaluation.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: 1
education and automated clinical alerts
|
automated clinical alerts in the electronic medical record
PCP education session on CKD
|
Active Comparator: 2
education session alone
|
PCP education session on CKD
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
referral to a nephrologist
Time Frame: 12 months
|
Referral to a nephrologist within the 12 months following decision support system activation.
|
12 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Use of ACE/ARB
Time Frame: 12 months
|
Active use of ACE/ARB at the end of the 12 month period following decision support system activation.
|
12 months
|
Annual ACR or PCR check
Time Frame: 12 months
|
ACR or PCR within 12months of the decision support system activation
|
12 months
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Khaled Abdel-Kader, MD, University of Pittsburgh
- Principal Investigator: Mark Unruh, MD, MSc, University of Pittsburgh
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- PRO07110299
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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