- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01220778
Effects of Physical Activity During Pregnancy on the Newborn's Cognitive Function
Effects of Physical Activity During Pregnancy on the Newborn's Cognitive Function, the Healthy Mom, Bright Child Randomized Trial
Background: It is now generally accepted that an active lifestyle is beneficial for cognition, but can these benefits be transmitted for the active pregnant woman to her unborn child? This has been demonstrated in rats where the pups born of mothers who exercised during pregnancy had increased hippocampal neurogenesis and better memory and learning capabilities. Human studies tend to confirm this by looking at behavioral results, ie. better orientation and state regulation skills in newborns. The aim of the present study is to verify this on the electrophysiological level and to determine the effects of an active lifestyle during pregnancy on the newborn's brain development.
Methods: 60 pregnant women will be included in a randomized controlled trial. The exercise group will be asked to exercise a minimum of 20 minutes, 3 times per week, at a minimal intensity of 55% of their maximal aerobic capacity. The control group will not be given exercise counselling. Newborns' brain activity will be recorded using electroencephalography (EEG) 10 days post partum. The primary outcome measure will be the amplitude and latency of the mismatch negativity (MMN), a component of the auditory event-related potential (ERP) that can be used to investigate the auditory sensory memory.
Study Overview
Study Type
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Elise L. LeMoyne
- Phone Number: 5380 514-343-6111
- Email: apgrossesse@kinesio.umontreal.ca
Study Locations
-
-
Quebec
-
Montreal, Quebec, Canada, H3T1J4
- Recruiting
- Cepsum
-
Contact:
- Elise L.LeMoyne
- Phone Number: 5380 514-343-6111
- Email: apgrossesse@kinesio.umontreal.ca
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- First trimester of pregnancy
- 20 to 35 years of age
- Pre-pregnancy BMI between 18 and 25
- Primipara
- Without any known health issues
- Use of folic acid
Exclusion Criteria:
- Use of alcohol, cigarettes or illegal drugs
- Pregnancy complications
- Unable or unwilling to breastfeed
- Excessive or insufficient weight gain
Study Plan
How is the study designed?
Design Details
- Allocation: Randomized
- Interventional Model: Parallel Assignment
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
No Intervention: Control
|
|
Experimental: Exercise
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
---|
Mismatch negativity
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Elise L.LeMoyne, Université de Montréal
Publications and helpful links
Helpful Links
Study record dates
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- CERSS-2010-951-P
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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