Stiffness Measurement of Liver Tumors and Visceral Parenchyma

May 17, 2011 updated by: China Medical University Hospital

Clinical Applications of Acoustic Radiation Force Impulse Technology in Stiffness Measurement of Liver Tumors and Visceral Parenchyma

The investigators are measuring hepatocellular carcinoma(HCC)stiffness using Acoustic Radiation Force Impulse (ARFI) technique to enhance the diagnostic accuracy for HCC stratifications and treatment efficacy.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

Regression modelings as well as validity testings including cut-off identification will be acquired by performing both qualitative and quantitative measurements of HCC using reference diagnostic modalities e.g. pathology grading, dynamic CT scanning, etc.

Study Type

Observational

Enrollment (Anticipated)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taichung, Taiwan, 40447
        • Recruiting
        • Hepatogastroenterology, Department of Internal Medicine, China Medical University Hospital
        • Contact:
        • Principal Investigator:
          • Sheng-Hung Chen, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

subjects with hepatocellular carcinoma(HCC)

Description

Inclusion Criteria:

with HCC

Exclusion Criteria:

  • subjects with liver cancer other than HCC
  • subjects with treated HCC
  • post major abdominal surgery
  • contraindications to liver tumor biopsy
  • contraindications to local percutaneous treatment of liver tumors
  • ARFI measurement low quality

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
newly diagnosed HCC
  • Subjects with newly diagnosed untreated hepatocellular carcinoma (HCC) will be enrolled.
  • Subjects with the following conditions will be excluded:

liver cancer other than HCC, treated HCC, post major abdominal surgery, contraindications to liver tumor biopsy, contraindications to local percutaneous treatment of liver tumors, low quality ARFI measurement
Other: stiffness measurement using ARFI
Stiffness measurement will be performed for HCC using ARFI technique.
Other Names:
  • Acuson S2000

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

China Medical University Hospital

Investigators

  • Principal Investigator: Sheng-Hung Chen, MD, Hepatogastroenterology, Department of Internal Medicine, China Medical University Hospital
  • Study Director: Cheng-Yuan Peng, MD,PhD, Hepatogastroenterology, Department of Internal Medicine, China Medical University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2011

Primary Completion (Anticipated)

March 1, 2012

Study Completion (Anticipated)

March 1, 2012

Study Registration Dates

First Submitted

April 26, 2011

First Submitted That Met QC Criteria

April 27, 2011

First Posted (Estimate)

April 28, 2011

Study Record Updates

Last Update Posted (Estimate)

May 18, 2011

Last Update Submitted That Met QC Criteria

May 17, 2011

Last Verified

May 1, 2011

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • DMR100-IRB-055

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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