Eating Disorders in Type 1 Diabetes: Mechanisms of Comorbidity

Eating Disorders in Type 1 Diabetes: Mechanisms of Comorbidity

Sponsors

Lead sponsor: Duke University

Collaborator: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Source Duke University
Brief Summary

The purpose of the study is to investigate how people with type 1 diabetes experience and manage their diabetes, eating, and weight. Summary of the Study: If you choose to participate, you will complete a set of questionnaires and a structured interview. You will then wear a continuous glucose monitor and use your cell phone to answer study questions for a period of 3 days. The questions come in the form of regular phone calls between the hours of 8:00 a.m. and 10:00 p.m. Each call takes only a minute or two to complete. You will also be asked to call in and answer study questions at other times during the day, especially after eating. The study involves a minimum of 2 clinic visits to Duke. Participants who live greater than 1.5 hours from Duke can be approved to take part in the study by phone/Skype. Participants will receive and return study materials through the mail.

Detailed Description

Eating disorders (ED) are far more prevalent among individuals with type 1 diabetes (T1D) than the general population. Yet what accounts for the increased prevalence of ED in T1D, and how to effectively treat these patients is unknown. ED in T1D is dangerous. T1D patients with ED not only engage in behaviors common among non-diabetic ED patients (like binge eating), but also might omit insulin to prevent weight gain. The goal of this study is to understand the psychophysiological precipitants to ED behavior among T1D patients.

Overall Status Completed
Start Date December 2011
Completion Date August 2014
Primary Completion Date August 2014
Study Type Observational
Primary Outcome
Measure Time Frame
Blood Glucose Values 72 Hours
Secondary Outcome
Measure Time Frame
Ecological Momentary Assessment of Emotional and Behavioral Outcomes 72 hours
Enrollment 83
Condition
Eligibility

Sampling method: Non-Probability Sample

Criteria:

Inclusion Criteria:

1. Adult (aged 18-65)

2. Diagnosed with type 1 diabetes

3. Clinically significant eating disorder symptoms

4. Currently monitored by a physician

Exclusion:

1. Severe hypoglycemic unawareness

2. Pregnancy

3. Current or history of psychosis or mania

4. Current substance abuse

5. Non-English speaking

6. Significant deficits in intellectual functioning

Gender: All

Minimum age: 18 Years

Maximum age: 65 Years

Healthy volunteers: Accepts Healthy Volunteers

Overall Official
Last Name Role Affiliation
Rhonda Merwin, PhD Principal Investigator Site Principal Investigator
Location
facility Duke University Health System
Location Countries

United States

Verification Date

August 2014

Responsible Party

Responsible party type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Study Design Info

Observational model: Cohort

Time perspective: Cross-Sectional

Source: ClinicalTrials.gov