- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01807195
Acute Renal Injury Associated Contrast in Intensive Care Unit Patients
June 5, 2014 updated by: Yonsei University
Generally, a contrast medium is used when performing a CT scan or radiographic tests such as angiography because it heightens image clarity and can increase diagnosis accuracy.
Despite these advantages, contrast media can cause allergic reactions in the body or a decline in renal function.
Therefore, they should be handled carefully and explained sufficiently to the patient.
For intensive care patients, the use of contrast agents has been revealed as a major cause of acute renal damage, and many studies have investigated this complication by examining incidence rates and prevention strategies.
Hypothesis: Among intensive care patients, the group in which a contrast medium was used will have a higher risk of renal function decline compared with the group in which a contrast medium was not used, and, hence, the use of contrast media becomes a cause of renal function deterioration.
Categorizing patients with renal function decline according to the new RIFLE criteria can have an association with the prognosis of intensive care patients, such as hospitalization period and death rate, which can promote faster intervention.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Actual)
886
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Seoul, Korea, Republic of, 120-752
- Department of anesthesiology and pain medicine
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) categorization and the existing classification method were used to compare their predictive value for acute renal damage related to contrast media.
Description
Inclusion Criteria:
- For the 5 years from January 2008 to December 2012, patients in whom a contrast medium was used in the intensive care unit were examined.
Exclusion Criteria:
- For the 5 years from January 2008 to December 2012, patients in whom a contrast medium was not used in the intensive care unit were examined.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
the medical records of those in whom a contrast medium
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The incidence of acute renal damage associated with contrast media in intensive care patients
Time Frame: each time evaluation of contrast medium usage
|
The occurrence of acute renal damage was examined, and these patients were compared with the group that did not develop acute renal damage to investigate whether the use of contrast agents acts as an independent variable.
In addition, the RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) categorization and the existing classification method were used to compare their predictive value for acute renal damage related to contrast media.
|
each time evaluation of contrast medium usage
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 2013
Primary Completion (Actual)
February 1, 2014
Study Completion (Actual)
February 1, 2014
Study Registration Dates
First Submitted
March 6, 2013
First Submitted That Met QC Criteria
March 7, 2013
First Posted (Estimate)
March 8, 2013
Study Record Updates
Last Update Posted (Estimate)
June 6, 2014
Last Update Submitted That Met QC Criteria
June 5, 2014
Last Verified
June 1, 2014
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 4-2012-0922
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Acute Renal Injury
-
InCor Heart InstituteUnknownAcute Kidney Injury | Acute Renal Failure | Acute Renal InjuryBrazil, Spain
-
Instituto Nacional de Cardiologia Ignacio ChavezInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranUnknownKidney Injury, Acute | Acute Renal Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Acute Renal InjuriesMexico
-
University of CologneFresenius KabiCompletedAcute Kidney Injury | Acute Renal FailureGermany
-
Quark PharmaceuticalsTerminatedAcute Kidney Injury | Acute Renal FailureUnited States
-
University of WashingtonJohns Hopkins University; National Institute of Diabetes and Digestive and... and other collaboratorsRecruitingChronic Kidney Diseases | Acute Renal Failure | Acute Renal Injury | Acute Kidney Failure | Chronic Renal Insufficiency | Kidney Failure, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiency | Acute Kidney Insufficiency | Renal Failure, Acute | Chronic Kidney Insufficiency | Chronic Renal Diseases | Kidney... and other conditionsUnited States
-
Istanbul UniversityCompleted
-
The Royal Wolverhampton Hospitals NHS TrustCompletedAcute Renal InjuryUnited Kingdom
-
Gachon University Gil Medical CenterCompleted
-
University Hospital, Clermont-FerrandRecruitingAcute Kidney Injury | Transient Acute Renal Failure | Persistent Acute Renal FailureFrance
-
Quark PharmaceuticalsCompletedAcute Renal Failure | Injury of KidneyUnited States, Israel, Switzerland
Clinical Trials on contrast medium usage
-
Sun Yat-sen UniversityCompletedContrast Induced NephropathyChina
-
Shaare Zedek Medical CenterUnknown
-
M.D. Anderson Cancer CenterRecruitingBreast CarcinomaUnited States
-
Seoul National University HospitalCompletedHepatocellular CarcinomaKorea, Republic of
-
Fondazione Policlinico Universitario Agostino Gemelli...Enrolling by invitationAortic Valve Stenosis | Heart Valve Diseases | Aortic Regurgitation | Aortic Valve Insufficiency | Aortic Stenosis, Severe | Regurgitation, Aortic | Stenoses, Aortic | Coronary; Obstruction | Valve Disease, AorticItaly
-
Rutgers, The State University of New JerseyNational Cancer Institute (NCI)RecruitingMetastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage... and other conditionsUnited States
-
Hospital Clinic of BarcelonaCompletedCardiovascular DiseaseSpain
-
University of Southern CaliforniaNational Cancer Institute (NCI)CompletedBreast CarcinomaUnited States
-
IRCCS San RaffaeleCompleted
-
Stanford UniversityWithdrawnLiver Transplantation | Renal Insufficiency, Chronic | Acute Kidney Injury | Contrast-induced Nephropathy | Contrast MediaUnited States