Effect of Medium Chain Triglyceride Consumption on Appetite (MCT)

September 27, 2013 updated by: Marie-Pierre St-Onge, St. Luke's-Roosevelt Hospital Center
The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

17

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • New York
      • New York, New York, United States, 10025
        • New York Obesity Nutrition Research Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 50 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Males
  • Weight stable (<10 lb over previous 3 months)
  • Overweight (body mass index 25-29.9)

Exclusion Criteria:

  • Smokers
  • Excessive caffeine users
  • Severe health conditions
  • Allergy to food products/ingredients in the study
  • Taking medications known to affect energy expenditure or gastrointestinal function

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Allocation: RANDOMIZED
  • Interventional Model: CROSSOVER
  • Masking: SINGLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
ACTIVE_COMPARATOR: MCT
MCT oil (20 g) was included in the test breakfast
Dietary supplement: Test breakfast
PLACEBO_COMPARATOR: LCT
Corn oil (20 g) was included in the test breakfast
Dietary supplement: Test breakfast

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Food intake
Time Frame: up to 3 hours
Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)
up to 3 hours

Secondary Outcome Measures

Outcome Measure
Time Frame
Ghrelin
Time Frame: 3 hours
3 hours
Peptide YY
Time Frame: 3 hours
3 hours
Glucagon-like peptide 1
Time Frame: 3 hours
3 hours
Insulin
Time Frame: 3 hours
3 hours
Triglycerides
Time Frame: 3 hours
3 hours
Leptin
Time Frame: 3 hours
3 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

St. Luke's-Roosevelt Hospital Center

Investigators

  • Principal Investigator: Marie-Pierre St-Onge, Ph.D, New York Obesity Nutrition Research Center

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2010

Primary Completion (ACTUAL)

August 1, 2011

Study Completion (ACTUAL)

August 1, 2011

Study Registration Dates

First Submitted

September 25, 2013

First Submitted That Met QC Criteria

September 27, 2013

First Posted (ESTIMATE)

September 30, 2013

Study Record Updates

Last Update Posted (ESTIMATE)

September 30, 2013

Last Update Submitted That Met QC Criteria

September 27, 2013

Last Verified

September 1, 2013

More Information

Terms related to this study

Other Study ID Numbers

  • MCT_1

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Obesity

Clinical Trials on Test breakfast

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Africa

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe