- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02080676
Effects of Marihuana Use on Optic Nerve Parameters and Ocular Blood Flow
Study Overview
Status
Conditions
Detailed Description
Purpose of study: to check the effect of medical cannabis given for approved medical indications on ocular parameters including intra ocular pressure, Retinal Nerve Fiber Layer (RNFL) thickness, optic nerve fibers thickness and choroidal thickness.
Adult patients with no ocular pathology that are being treated in the neurology or pain clinics with medical cannabis for different indications, were examined in the eye clinic.
First examination took place after the patient was not smoking for 5 hours. Three more examinations took place 1 hour 3 hours and 5 hours after smoking cannabis.
The following parameters were checked: blood pressure, pulse, visual acuity, intra ocular pressure, corneal thickness, axial length, slit lamp examination of anterior segment, fundoscopy and Optical Coherence Tomography (OCT) of the retina, and optic nerve.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Orna Geyer, MD
- Phone Number: 97248250926
- Email: orna_geyer@clalit.org.il
Study Locations
-
-
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Haifa, Israel
- Recruiting
- Carmel Medical Center
-
Contact:
- Nurit Mathalone, MD
- Phone Number: 97248250477
- Email: Nurit.Mathalone@clalit.org.il
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Principal Investigator:
- Orna Geyer, MD
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Age over 18
- Treated with medical cannabis for approved medical indications
Exclusion Criteria:
- Known ocular pathology
- Topical or systemic treatment for intra ocular pressure
- Previous topical, intra ocular or systemic steroid treatment
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Intra ocular pressure
Time Frame: 5 hours
|
5 hours
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- CMC-14-0001-CTIL
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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