Mobility & Vitality Lifestyle Program (MOVE UP)

Health Promotion and Disease Prevention Research Center

MOVE UP is a weight management program for adults 60-75 in community settings led by trained community health workers.

Study Overview

• Status: Completed
• Conditions: Obesity
• Intervention / Treatment: Behavioral: MOVE UP

Detailed Description

MOVE UP is a weight management program designed for adults who desire to lose weight and improve their overall health.

Topics include: Overall Health, Weight management, Healthy eating, Behavior change, Physical activity

• Study Type: Interventional
• Enrollment (Actual): 303
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Pennsylvania
    • Pittsburgh, Pennsylvania, United States
      • Community Sites

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 60 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

1. Age 60-75 at time of program start
2. Self-reporting < 60 minutes per week of moderate structured physical activity
3. BMI >= 30 but < 40 for screen. In person measurement on site will allow for 27-45 as inclusion criteria.
4. Able to consent for participation and data collection
5. Medical release before start of Weight Management
6. Ability to walk with or without an assistive device
7. Can regularly attend sessions
8. Has not had bariatric surgery over the past year, or current use of weight loss prescription drug.

Exclusion Criteria:

1. Uncontrolled diabetes mellitus (FBS > 300 & A1C > 11%) [to be assessed by physician on medical release]
2. Uncontrolled hypertension (SBP > 180/110) %) [to be assessed by physician on medical release]
3. Recent hospitalization (past 6 months)
4. Active treatment for cancer (other than non-melanoma skin cancer)
5. Significant visual or hearing impairment
6. Dementia/psychiatric disorder
7. Inability to communicate in English/lack of translator

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: MOVE UP Intervention; Subjects will participate in a healthy lifestyle weight management intervention focused on healthy eating and increasing physical activity	Behavioral: MOVE UP; Weight management behavioral program

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Short Physical Performance Battery	Physical function objectively measured by Short Physical Performance Battery (SPPB) which includes gait speed, grip strength and chair stands, each ranked as 0-4 and summed for a total score of 0-12 units	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Self-reported Physical Function	Physical function self-reported with the MOS-SF36 - questions are assigned points for total points ranging fom 0-36	1 year
Weight	Weight in kilograms	1 year
Height	Height measured in meters	1 year
BMI	Calculated from objective measurements of height and weight above as weight in Kilograms divided height in meters-squared	1 year

Collaborators and Investigators

• Sponsor: University of Pittsburgh
• Collaborators: Centers for Disease Control and Prevention
• Investigators: Principal Investigator: Anne B. Newman, MD, University of Pittsburgh

Publications and helpful links

General Publications

• Liu X, King J, Boak B, Danielson ME, Boudreau RM, Newman AB, Venditti EM, Albert SM. Effectiveness of a behavioral lifestyle intervention on weight management and mobility improvement in older informal caregivers: a secondary data analysis. BMC Geriatr. 2022 Jul 28;22(1):626. doi: 10.1186/s12877-022-03315-w.

Study record dates

Study Major Dates

• Study Start (Actual): May 4, 2015
• Primary Completion (Actual): July 18, 2019
• Study Completion (Actual): July 18, 2019

Study Registration Dates

• First Submitted: November 25, 2015
• First Submitted That Met QC Criteria: January 13, 2016
• First Posted (Estimate): January 15, 2016

Study Record Updates

• Last Update Posted (Actual): January 14, 2020
• Last Update Submitted That Met QC Criteria: January 10, 2020
• Last Verified: January 1, 2020

More Information

Terms related to this study

• Keywords: Physical Function
• Other Study ID Numbers: 1U48DP005001-01 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No