Influence of Myocardial Shortening on Coronary Tortuosity

September 26, 2016 updated by: Jonathan R. Lindner, MD, Oregon Health and Science University

Determinants of Coronary Tortuosity

This study is a retrospective analysis where coronary arteriograms are being analyzed to determine whether the presence of tortuous coronary arteries correlate with any specific measures of left ventricular mass or left ventricular function on echocardiography.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

70

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Oregon
      • Portland, Oregon, United States, 97239
        • OHSU

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 90 years (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Retrospective study of subjects who have undergone clinically-indicated coronary arteriography who also have an echocardiogram that was performed within 3 months of the angiogram.

Description

Inclusion Criteria:

  • subjects referred for angiography
  • echocardiography performed within 3 months.

Exclusion Criteria:

  • connective tissue disease
  • severe LV dysfunction
  • prior coronary artery bypass surgery
  • major adverse coronary event between angiogram and echo procedures
  • moderate or greater valve disease
  • acute coronary syndrome

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Normal coronary arteries
Patients in whom coronary arteriography has demonstrated no significant tortuosity.
Other: No intervention. Observational study
No intervention
Tortuous coronary arteries
Patients in whom coronary arteriography has demonstrated tortuous coronary arteries defined as >1 major bend of >45 degrees in a major coronary artery
Other: No intervention. Observational study
No intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Degree of longitudinal shortening
Time Frame: 3 months
Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram
3 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
LV mass
Time Frame: 3 months
Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram
3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Oregon Health and Science University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2015

Primary Completion (ACTUAL)

September 1, 2016

Study Completion (ACTUAL)

September 1, 2016

Study Registration Dates

First Submitted

April 13, 2016

First Submitted That Met QC Criteria

April 15, 2016

First Posted (ESTIMATE)

April 18, 2016

Study Record Updates

Last Update Posted (ESTIMATE)

September 27, 2016

Last Update Submitted That Met QC Criteria

September 26, 2016

Last Verified

September 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Coronary Tortuosity

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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