Individualizing Disease Prevention for Middle-Aged Adults

March 30, 2022 updated by: Glen Taksler
The primary objective of this study is to help patients compare the benefits of various preventive care services, based on their individual risk factors (such as smoking status, obesity, high blood pressure, high cholesterol, etc.). A tailored decision tool will be provided to each participant during primary care appointments to facilitate discussion between the participant and his/her provider regarding prioritizing preventive service recommendations.

Study Overview

Status

Terminated

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

104

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Ohio
      • Cleveland, Ohio, United States, 44195
        • Cleveland Clinic

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

45 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Scheduled for an appointment with primary care provider during study period
  • Two or more of the following risk factors:
  • Tobacco use
  • Overweight/obese
  • Hypertension
  • Hyperlipidemia
  • Diabetes
  • Alcohol Misuse
  • Depression
  • History of Sexually Transmitted Infection
  • Being overdue for the following screenings: Colorectal, cervical, breast, lung

Exclusion Criteria:

- Severely limited life expectancy (cancer, congestive heart failure, chronic obstructive pulmonary disease, end stage renal disease)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Control
Usual care
Experimental: Intervention
Individualized preventive care recommendations will be distributed to subjects.
Other: Intervention
Written material provided.
Experimental: Development Phase
Non-randomized receipt of individualized preventive care recommendations
Other: Intervention
Written material provided.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Interest in Individualized Preventive Care Recommendations.
Time Frame: Within 3 days of index primary care appointment.

Measured by individualized preventive service recommendations, tailored to patient's specific medical conditions. Measured by surveys.

Survey question: "Overall, how helpful did you find the written materials (handouts)?" Ten point scale (minimum 1, maximum 10, higher score is better outcome)
Within 3 days of index primary care appointment.
Interest in Individualized Preventive Care Recommendations.
Time Frame: Within 3 days of index primary care appointment.

Measured by individualized preventive service recommendations, tailored to patient's specific medical conditions. Measured by surveys.

Survey question: "In the future, would you like to see updated written materials (handouts)?" Ten point scale (minimum 1, maximum 10, higher score is better outcome)
Within 3 days of index primary care appointment.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Use of Shared Decision Making.
Time Frame: Within 3 days of index primary care appointment.
Measured by surveys. Survey metric: Shared Decision Making (SDM)-Q-9 validated scale, converted to 100 point denominator 100 point scale (minimum 1, maximum 100, higher score is better outcome)
Within 3 days of index primary care appointment.
Patient Readiness to Change Health Behaviors.
Time Frame: Within 3 days of index primary care appointment.
Measured by surveys. Proportion of top-3 individualized preventive service recommendations ready to change over next 1 month Numerator: Number of top-3-ranked recommendations with score >=6 out of 7 on Likert scale for readiness to change over next 1 month (minimum=1, maximum=7, higher score was better) Denominator: The number of individualized preventive service recommendations provided to a patient or 3, whichever was lower
Within 3 days of index primary care appointment.
Patient Readiness to Change Health Behaviors
Time Frame: Within 3 days of index primary care appointment
Measured by surveys Proportion of top-3 individualized preventive service recommendations ready to change over next 2-6 months Numerator: Number of top-3-ranked recommendations with score >=6 out of 7 on Likert scale for readiness to change over next 2-6 months (minimum=1, maximum=7, higher score was better) Denominator: The number of individualized preventive service recommendations provided to a patient or 3, whichever was lower
Within 3 days of index primary care appointment
Patient Readiness to Change Health Behaviors.
Time Frame: Within 3 days of index primary care appointment
Measured by surveys Proportion of bottom-3 individualized preventive service recommendations ready to change over next 1 month Numerator: Number of bottom-3-ranked recommendations with score >=6 out of 7 on Likert scale for readiness to change over next 1 month (minimum=1, maximum=7, higher score was better) Denominator: The number of individualized preventive service recommendations provided to a patient or 3, whichever was lower
Within 3 days of index primary care appointment
Patient Readiness to Change Health Behaviors
Time Frame: Within 3 days of index primary care appointment
Measured by surveys. Proportion of bottom-3 individualized preventive service recommendations ready to change over next 2-6 months Numerator: Number of bottom-3-ranked recommendations with score >=6 out of 7 on Likert scale for readiness to change over next 2-6 months (minimum=1, maximum=7, higher score was better) Denominator: The number of individualized preventive service recommendations provided to a patient or 3, whichever was lower
Within 3 days of index primary care appointment
Decisional Comfort.
Time Frame: Within 3 days of index primary care appointment.
Measured by surveys. Survey metric: Decisional Conflict Scale (validated scale), converted to 100 point denominator 100 point scale (minimum 1, maximum 100, higher score is better outcome)
Within 3 days of index primary care appointment.
Preventive Care Outcomes for Patients.
Time Frame: Within 1 year of index primary care appointment.
Number of participants with at least 1 follow-up encounter during the 1 year after an index encounter.
Within 1 year of index primary care appointment.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Glen Taksler

Collaborators

National Institute on Aging (NIA)

Investigators

  • Principal Investigator: Glen Taksler, PhD, The Cleveland Clinic

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 22, 2017

Primary Completion (Actual)

March 12, 2020

Study Completion (Actual)

March 12, 2021

Study Registration Dates

First Submitted

January 13, 2017

First Submitted That Met QC Criteria

January 13, 2017

First Posted (Estimate)

January 18, 2017

Study Record Updates

Last Update Posted (Actual)

April 26, 2022

Last Update Submitted That Met QC Criteria

March 30, 2022

Last Verified

March 1, 2022

More Information

Terms related to this study

Other Study ID Numbers

  • 16-854

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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