Diode Laser Therapy As An Adjunct To Scaling And Root Planing

Diode Laser Therapy As An Adjunct To Non-Surgical Management Of Chronic Periodontitis - A Pilot Study

Laser therapy has been proposed as a novel treatment option in controlling subgingival microorganisms. This randomized controlled clinical trial evaluates the effect of 980nm diode laser as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis (CP).

Study Overview

• Status: Completed
• Conditions: Chronic Periodontitis
• Intervention / Treatment: Procedure: Ultrasonic Scaling and root planing; Procedure: 980 nm diode laser irradiation

Detailed Description

Conventional mechanical debridement can achieve a temporary decrease in the subgingival levels of Pg along with other pathogens. However, mechanical therapy alone may fail to eliminate pathogenic bacterial niches in inaccessible areas like deep pockets, root concavities, furcation areas etc. In search of more efficient and less traumatic techniques to improve periodontal healing, researchers proposed the use of lasers in periodontal therapy.

The adjunctive use of lasers with conventional tools may facilitate treatment and have the potential to improve healing. The diode laser is highly absorbed in hemoglobin and other pigments and is excellent for use in soft tissue surgical procedures.Laser application in improving clinical outcome in periodontal therapy, needs to be further investigated with well designed clinical trials. The investigators attempted to evaluate the efficacy of diode laser as an adjunct to SRP in the management of CP by evaluating clinical parameters coupled with quantitative estimation of P.gingivalis using Real-time Polymerase chain reaction (RT-PCR) assay.

• Study Type: Interventional
• Enrollment (Actual): 40
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 30 years to 50 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• 40 systemically healthy subjects diagnosed with generalized moderate CP in the age group of 30 to 50 years.
• Minimum of 20 teeth having atleast two non-adjacent sites per quadrant with probing pocket depth of ≥ 5mm and clinical attachment loss of 3- 4 mm

Exclusion Criteria:

• Patients who had undergone periodontal therapy 6 months prior to the commencement of the study.
• Subjects on antibiotics or immunosuppressants.
• Chronic smokers, alcoholics, smokeless tobacco users.
• Subjects with acute illnesses/acute intraoral lesions.
• Pregnant women
• Subjects who had undergone extensive restorative dental treatment.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Ultrasonic Scaling, Root planing; Ultrasonic Scaling and Root planing at day 0 and at 1 week.	Procedure: Ultrasonic Scaling and root planing; Procedure of scaling and root planing at day 0 and at 1 week
Experimental: 980 nm diode Laser irradiation; Irradiation of periodontal pockets with with 980 nm diode Laser after scaling and root planing at day 0 and after 1 week.	Procedure: Ultrasonic Scaling and root planing; Procedure of scaling and root planing at day 0 and at 1 week; Procedure: 980 nm diode laser irradiation; Procedure of scaling and root planing and application of 980 nm diode laser at day 0 and at 1 week

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in levels of P.gingivalis	Microbial profile was assessed using PCR at baseline, 4-6 weeks and 12-14 weeks post treatment in both the study groups.	14 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in gingival index	Gingival index by Loe and Silness was assessed at baseline, 4-6 weeks and 12-14 weeks post treatment in both the groups	14 weeks
Change in plaque index	Plaque index by Silness and Loe was assessed at baseline, 4-6 weeks and 12-14 weeks	14 weeks
Change in probing pocket depth	Probing pocket depth was assessed at baseline, 4-6 weeks and 12-14 weeks	14 weeks
Change in clinical attachment level	Clinical attachment level was assessed at baseline, 4-6 weeks and 12-14 weeks	14 weeks

Collaborators and Investigators

• Sponsor: KLE Society's Institute of Dental Sciences

Study record dates

Study Major Dates

• Study Start: March 1, 2013
• Primary Completion (Actual): September 1, 2013
• Study Completion (Actual): September 1, 2013

Study Registration Dates

• First Submitted: January 7, 2017
• First Submitted That Met QC Criteria: January 19, 2017
• First Posted (Estimate): January 23, 2017

Study Record Updates

• Last Update Posted (Estimate): January 23, 2017
• Last Update Submitted That Met QC Criteria: January 19, 2017
• Last Verified: January 1, 2017

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Stomatognathic Diseases; Periodontal Diseases; Mouth Diseases; Periodontitis; Chronic Periodontitis
• Other Study ID Numbers: KLESocietyIDS

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No