BLITZ Heart Failure (BLITZ-HF)

July 22, 2019 updated by: Heart Care Foundation
To evaluate if Italian Cardiologists are treating Heart Failure (HF) patients according to International guidelines and if a structured educational program can improved their adherence.

Study Overview

Status

Completed

Conditions

Detailed Description

Multicentre, cross-sectional, prospective, non-interventional, observational study designed to evaluate the level of adherence to current ESC guidelines recommendations in both acute and chronic HF patients enrolled in each participating center and to verify if a specific HF educational intervention composed by an educational web based program of data collection and face to face meetings is able to improve adherence to guidelines recommendations evaluated during a second enrollment period.

Study Type

Observational

Enrollment (Actual)

7569

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Italy
      • Frattamaggiore, Italy, 80027
        • Ospedale San Giovanni Di Dio - Uo Cardiologia - Utic
      • Giugliano In Campania, Italy, 80014
        • Ospedale Generale Di Zona - U.O. Cardiologia - Utic
      • Napoli, Italy, 80131
        • Aou Federico Ii - Uoc Cardiologia E Utic
      • Nola, Italy, 80035
        • Pres. Ospedaliero S. Maria Della Pieta' - U.O. Cardiologia E Utic
      • Pescia, Italy, 51017
        • Ospedale Della Val Di Nievole - U. O. Cardiologia - Utic
      • Pistoia, Italy, 51100
        • Ospedale San Jacopo - U.O. Cardiologia
      • San Giuseppe Vesuviano, Italy, 80047
        • Casa Di Salute Santa Lucia - U.O. Cardiologia
    • AN
      • Ancona, AN, Italy, 60122
        • Ospedali Riuniti - Sod Cardiologia Ospedaliera Emod. E Utic
    • AO
      • Aosta, AO, Italy, 11100
        • Ospedale Generale Regionale-Po U. Parini - U.O. Cardiologia E Cure Intensive Card.
    • AP
      • Ascoli Piceno, AP, Italy, 63100
        • Ospedale Gen.Le Prov.Le C.G. Mazzoni - Sc Cardiologia
    • AR
      • Cortona, AR, Italy, 52044
        • Ospedale Valdichiana Santa Margherita - Uos Cardiologia E Hdu
    • AV
      • Avellino, AV, Italy, 83100
        • Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'
    • BG
      • Bergamo, BG, Italy, 24127
        • Asst Papa Giovanni Xxiii - Cardiologia 1
      • Seriate, BG, Italy, 24068
        • Ospedale Bolognini - Cardiologia E Unita' Coronarica
      • Treviglio, BG, Italy, 24047
        • Ospedali Treviglio-Caravaggio - Cardiologia
    • BL
      • Feltre, BL, Italy, 32032
        • Ospedale Santa Maria Del Prato - U.O. Di Cardiologia
    • BO
      • Bologna, BO, Italy, 40133
        • Ospedale Maggiore - U.O. Di Cardiologia
      • Bologna, BO, Italy, 40139
        • Ospedale Bellaria - U.O. Di Cardiologia
      • Bologna, BO, Italy, 40138
        • Ospedale Policlinico S. Orsola-Malpighi - Medicina Interna - Borghi
    • BR
      • Brindisi, BR, Italy, 72100
        • Ospedale Perrino - U.O.C. Di Cardiologia
    • BS
      • Brescia, BS, Italy, 25123
        • Spedali Civili - Cardiologia
      • Brescia, BS, Italy, 25124
        • Istituto Osped. Fondazione Poliambulanza - Unita' Operativa Di Cardiologia
      • Gavardo, BS, Italy, 25085
        • Ospedale Civile 'La Memoria' - U.O. Di Cardiologia
      • Lumezzane, BS, Italy, 25065
        • Ics Maugeri Spa Societa' Benefit - U.O. Di Cardiologia Riabilitativa
    • BT
      • Barletta, BT, Italy, 76121
        • Ospedale Monsignor Angelo R. Di Miccoli - Unita' Operativa Di Cardiologia
      • Bisceglie, BT, Italy, 76011
        • Ospedale Vittorio Emanuele Ii - Cardiologia
    • CA
      • Cagliari, CA, Italy, 09134
        • Azienda Ospedaliera G. Brotzu - Struttura Complessa Di Cardiologia
    • CE
      • San Felice A Cancello, CE, Italy, 81027
        • Ospedale Ave Gratia Plena - Uosd Riabilitazione Cardiologica
      • Santa Maria Capua Vetere, CE, Italy, 81055
        • Ospedale San Giuseppe E Melorio U.O.C. Cardiologia Utic
    • CO
      • San Fermo Della Battaglia, CO, Italy, 22020
        • Ospedale S. Anna - U.O.C. Di Cardiologia
    • CR
      • Crema, CR, Italy, 26013
        • Ospedale Maggiore - U.O. Cardiologia E Utic
      • Cremona, CR, Italy, 26100
        • Ospedale Di Cremona - Uo Di Cardiologia
    • CT
      • Catania, CT, Italy, 95122
        • P.O. Garibaldi-Nesima - U.O.C. Di Cardiologia
      • Catania, CT, Italy, 95124
        • P.O. Garibaldi Centro - U.O.C. Cardiologia
      • Catania, CT, Italy, 95125
        • Policlinico Catania Po G. Rodolico - Ssd Scompenso Cardiaco Grave
    • CZ
      • Lamezia Terme, CZ, Italy, 88046
        • Ospedale Giovanni Paolo Ii - U.O. Cardiologia E Utic
    • FC
      • Cesena, FC, Italy, 47023
        • Ospedale M.Bufalini - U.O. Di Cardiologia-Utic
      • Forlì, FC, Italy, 47100
        • Ospedale G.B. Morgagni - L. Pierantoni - U.O. Cardiologia
    • FE
      • Ferrara, FE, Italy, 44124
        • Arcispedale Sant'Anna - U.O. Cardiologia - Utic
    • FG
      • Foggia, FG, Italy, 71100
        • Ospedali Riuniti - S.C. Di Cardiologia Univ.-Utic
    • FI
      • Empoli, FI, Italy, 50053
        • Ospedale Civile San Giuseppe - Cardiologia
      • Firenze, FI, Italy, 50124
        • Ospedale San Giovanni Di Dio - Cardiologia
      • Firenze, FI, Italy, 50122
        • Ospedale Santa Maria Nuova - Hdu Cardiologica/Utic
      • Firenze, FI, Italy, 50141
        • Aou Careggi - Geriatria - Utig
    • FM
      • Fermo, FM, Italy, 63900
        • Ospedale Civile Augusto Murri - U.O. Cardiologia
    • GE
      • Genova, GE, Italy, 16153
        • Ospedale Padre Antero Micone - Sc Cardiologia - Utic
      • Genova, GE, Italy, 16132
        • Ospedale Policlinico San Martino - Unita' Operativa Cardiologia
      • Genova, GE, Italy, 16149
        • Ospedale Villa Scassi - Sc Cardiologia Utic
    • LC
      • Merate, LC, Italy, 23807
        • Ospedale San Leopoldo Mandic - Cardiologia - Ucc
    • LE
      • Copertino, LE, Italy, 73043
        • Ospedale San Giuseppe Da Copertino - U.O. Di Cardiologia-Utic
    • LU
      • Lido Di Camaiore, LU, Italy, 55043
        • Nuovo Ospedale Versilia - Sc Cardiologia
    • MB
      • Monza, MB, Italy, 20900
        • Policlinico Di Monza - Uo Cardiol. Clinica E Scompenso Cardiaco
      • Monza, MB, Italy, 20900
        • Ospedale San Gerardo - U.O. Cardiologia-Utic
    • ME
      • Messina, ME, Italy, 98124
        • Policlinico G. Martino - U.O. Medicina Interna
    • MI
      • Legnano, MI, Italy, 20025
        • Ospedale Civile - Uo Cardiologia
      • Milano, MI, Italy, 20153
        • Ospedale San Carlo Borromeo - Cardiologia-Ucc
      • Milano, MI, Italy, 20132
        • Ospedale San Raffaele - Cardiologia Clinica
      • Milano, MI, Italy, 20138
        • Centro Cardiologico Monzino - Cardiologia D'Urgenza
      • Milano, MI, Italy, 20159
        • Asst Ospedale Metropolitano Niguarda - Diagnosi E Cure Terr. Malattie Cardiache
      • Milano, MI, Italy, 20162
        • Asst Ospedale Metropolitano Niguarda - Cardiologia 1 - Emodinamica
      • Milano, MI, Italy, 20162
        • Asst Ospedale Metropolitano Niguarda - Cardiologia 2 -Insuff. Card. E Trapianto
      • Rho, MI, Italy, 27010
        • Presidio Ospedaliero Di Passirana - Uo Cardiologia Riabilitativa
      • Rozzano, MI, Italy, 20089
        • Istituto Clinico Humanitas - U.O. Cardiologia Clinica
    • MO
      • Carpi, MO, Italy, 41012
        • Ospedale Ramazzini - U.O. Cardiologia
      • Sassuolo, MO, Italy, 14049
        • Ospedale Di Sassuolo - Cardiologia
    • NU
      • Nuoro, NU, Italy, 08100
        • Ospedale San Francesco - Cardiologia - Utic
    • PA
      • Cefalù, PA, Italy, 90015
        • Fondazione G. Giglio - U.O. Cardiologia E Utic
    • PD
      • Piove Di Sacco, PD, Italy, 35028
        • Ospedale Civile Immacolata Concezione - Cardiologia E Utic
    • PG
      • Assisi, PG, Italy, 06081
        • Ospedale Di Assisi - Unita' Integrata Scompenso Cardiaco
      • Città Di Castello, PG, Italy, 06012
        • Presidio Ospedaliero Citta' Di Castello - U.O. Di Cardiologia
      • Perugia, PG, Italy, 06123
        • Ex Ospedale Grocco - Unita' Operativa Cres
      • Perugia, PG, Italy, 06129
        • Azienda Ospedaliera Di Perugia - Cardiologia E Fisiopat. Cardiovascolare
    • PI
      • Pisa, PI, Italy, 56124
        • Ftgm - Stabilimento Di Pisa - Cardiologia E Medicina Cardiovascolare
    • PN
      • Pordenone, PN, Italy, 33170
        • Ospedale Di Pordenone - S.O.C. Cardiologia
    • PV
      • Montescano, PV, Italy, 27040
        • Ics Maugeri Spa Societa' Benefit - Divisione Di Cardiologia Riabilitativa
      • Pavia, PV, Italy, 27100
        • Fondazione Irccs Policlinico San Matteo - Cardiologia
      • Pavia, PV, Italy, 27100
        • Ics Maugeri Spa Societa' Benefit - U.O. Di Riabilitazione Cardiologica
    • RA
      • Ravenna, RA, Italy, 48100
        • Ospedale Civile Santa Maria Delle Croci - U.O. Di Cardiologia
    • RE
      • Correggio, RE, Italy, 42015
        • Ospedale Civile San Sebastiano - Sos Cardiologia Area Nord
      • Guastalla, RE, Italy, 46016
        • Ospedale Civile - Sc Cardiologia Area Nord
      • Reggio Emilia, RE, Italy, 42100
        • Arcispedale Santa Maria Nuova - S.C. Cardiologia
    • RG
      • Ragusa, RG, Italy, 97100
        • Ospedale M.P. Arezzo - U.O.C. Cardiologia-Utic
    • RM
      • Albano Laziale, RM, Italy, 00040
        • Aslrm6-Polo H2 Albano-Genzano - U.O.C. Di Cardiologia E Utic
      • Anzio, RM, Italy, 00042
        • Ospedali Riuniti Anzio-Nettuno - U.O. Di Cardiologia - Utic
      • Pomezia, RM, Italy, 00040
        • Policlinico Citta' Di Pomezia S. Anna - U.O. Cardiologia-Utic
      • Roma, RM, Italy, 00135
        • P.O. San Filippo Neri - Asl Roma 1 - Uoc Cardiologia E Utic
      • Roma, RM, Italy, 00152
        • Ospedale San Camillo - Uoc Cardiologia 1
      • Roma, RM, Italy, 00161
        • Policlinico Umberto Primo - Malattie Cardiovascolari A
      • Roma, RM, Italy, 00193
        • Ospedale Santo Spirito - U.O.C. Di Cardiologia
      • Roma, RM, Italy, 00152
        • Clinica Citta' Di Roma - Cardiologia-Utic
      • Roma, RM, Italy, 00169
        • Policlinico Casilino - U.O. Cardiologia
      • Roma, RM, Italy, 00184
        • Ao San Giovanni Addolorata - Cardiologia E Riab. Cardiologica
    • RN
      • Riccione, RN, Italy, 47838
        • Ospedale G. Ceccarini - Cardiologia-Utic
      • Rimini, RN, Italy, 47900
        • Ospedale Infermi -U.O. Cardiologia
    • SA
      • Battipaglia, SA, Italy, 84091
        • Presidio Osped. S. Maria Della Speranza - U.O. Di Cardiologia
      • Eboli, SA, Italy, 84025
        • Ospedale Maria Ss. Addolorata - U.O. Di Cardiologia Utic
      • Salerno, SA, Italy, 84131
        • Aou S. Giovanni Di Dio-Ruggi D'Aragona - Cardiologia Interventistica - Emodinamic
    • SI
      • Poggibonsi, SI, Italy, 53036
        • Ospedale Dell'Alta Val D'Elsa Uosd Cardiologia-Utic
      • Siena, SI, Italy, 53100
        • Aou Senese Ospedale S. Maria Alle Scotte - U.O.C. Cardiologia Ospedaliera
    • SR
      • Augusta, SR, Italy, 96011
        • Ospedale E. Muscatello - U.O. Di Cardiologia - Utic
      • Avola, SR, Italy, 96012
        • Ospedale G. Di Maria - Cardiologia Utic
      • Lentini, SR, Italy, 96016
        • P.O. Lentini - U.O. Di Cardiologia Con Utic
    • TE
      • Teramo, TE, Italy, 64100
        • Ospedale Civile G. Mazzini - Cardiologia Utic Ed Emodinamica
    • TO
      • Ciriè, TO, Italy, 10073
        • Por Cirie'- Lanzo Presidio Cirie' - S.C. Cardiologia Cirie'- Ivrea
      • Ivrea, TO, Italy, 10015
        • Ospedale Civile - S.C. Cardiologia Cirie' Ivrea
      • Moncalieri, TO, Italy, 10024
        • Ospedale Santa Croce - Cardiologia
      • Orbassano, TO, Italy, 10043
        • Ospedale San Luigi Gonzaga - S.C.D.O. Cardiologia
      • Torino, TO, Italy, 10128
        • Ospedale Mauriziano Umberto I - Sc Cardiologia
      • Torino, TO, Italy, 10155
        • Ospedale Giovanni Bosco - Sc Cardiologia
      • Torino, TO, Italy, 10132
        • Maria Pia Hospital - Uo Medicina
    • TS
      • Trieste, TS, Italy, 34125
        • Asui Trieste - S.C. Centro Cardiovascolare
      • Trieste, TS, Italy, 34149
        • Ospedali Riuniti - Osp. Cattinara - S.O.C. Cardiologia
    • TV
      • Treviso, TV, Italy, 31100
        • Ospedale Ca' Foncello - U.O.C. Cardiologia
    • UD
      • Udine, UD, Italy, 33100
        • Pou Santa Maria Della Misericordia - S.O.C. Cardiologia
    • VA
      • Busto Arsizio, VA, Italy, 21052
        • Ospedale Di Circolo Di Busto Arsizio - Uoc Cardiologia Utic Emodinamica
      • Gallarate, VA, Italy, 21013
        • Ospedale S. Antonio Abate - U.O. Di Cardiologia
      • Saronno, VA, Italy, 21047
        • Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia
      • Varese, VA, Italy, 21100
        • Ospedale Di Circolo E Fondazione Macchi - Cardiologia I
    • VE
      • Chioggia, VE, Italy, 30019
        • Ospedale Civile - U.O.C. Cardiologia
      • Mirano, VE, Italy, 30035
        • Ospedale Civile - U.O. Cardiologia
    • VI
      • Arzignano, VI, Italy, 36071
        • Ospedale Civile - U.O.C. Cardiologia
    • VR
      • San Bonifacio, VR, Italy, 37047
        • Ospedale G. Fracastoro - U.O.C. Di Cardiologia
    • VV
      • Vibo Valentia, VV, Italy, 89900
        • Ospedale Civile G. Jazzolino - U.O. Cardiologia - Utic

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Hospitalized and ambulatory heart failure patients admitted to or evaluated in Italian Hospitals

Description

Inclusion Criteria:

  • All consecutive patients with chronic HF and those admitted for acute (de novo) or worsening chronic HF.
  • Chronic HF: any NYHA class (I-IV).
  • Acute HF Only patients in NYHA class III or IV, or with pulmonary edema or cardiogenic shock for whom an IV therapy specific for HF (diuretic, vasodilators, vasopressors) is administered.
  • Any gender.
  • Any etiology of HF.
  • Any level of EF.
  • Written informed consent.

Exclusion Criteria:

  • - Age <18 years.
  • Inclusion in registries or trials that can influence, by protocol, the clinical management of patients.
  • Patients already enrolled in the BLITZ HF (by another participating centre or in the first enrollment period).

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Adherence to current guideline
Time Frame: Enrollment
To assess number of patients managed and treated following the 2016 ESC Heart Failure Gudelines (acute HF, chronic HFrEF, chronic HFmrEF, chronic HFpEF).
Enrollment
Patients managed and treated following International Guideline
Time Frame: 24 months
Patients treatment in phase 1 versus phase 3
24 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mortality
Time Frame: 12 months Follow-up
Death from all-causes, for cardiovascular causes, for HF
12 months Follow-up
Morbidity
Time Frame: 12 months Follow-up
Hospital admissions from all-causes, for cardiovascular causes, for HF
12 months Follow-up
Indication to heart failure device implantation
Time Frame: Enrollement
The rate of patients with chronic HFrEF with an indication to ICD and/or CRT planned in clinical practice
Enrollement
Prescription rate of disease modifying drugs
Time Frame: Enrollment
The rate of patients with HFrEF receiving all the drugs recommended by current guidelines: ACE-Is/ARBs, betablockers and MRAs, in the absence of specific contraindications/intolerance.
Enrollment
Oral anticoagulation prescription in patients with AF
Time Frame: Enrollment
Rate of patients treated with oral anticoagulants in case of AF
Enrollment
Use of ARNI
Time Frame: Enrollment
The rate of implementation of a new drug approach (ARNI) for patients with HF and EF ≤35%
Enrollment
Creatinine and EF evaluation
Time Frame: Enrollment
The rate of CHF patients with an available measure of EF and of creatinine.
Enrollment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Heart Care Foundation

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

March 8, 2017

Primary Completion (ACTUAL)

July 2, 2019

Study Completion (ACTUAL)

July 2, 2019

Study Registration Dates

First Submitted

August 16, 2018

First Submitted That Met QC Criteria

September 4, 2018

First Posted (ACTUAL)

September 7, 2018

Study Record Updates

Last Update Posted (ACTUAL)

July 23, 2019

Last Update Submitted That Met QC Criteria

July 22, 2019

Last Verified

August 1, 2018

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • K15

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Heart Failure

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe