- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03754946
The Critical Threshold of Pulse Oximetry Plethysmographic Waveform Parameters in High Quality CPR
November 26, 2018 updated by: Peking Union Medical College Hospital
The purpose of this study is to analyze the relationship of the area under the curve (AUC) and/or the amplitude (Amp) of pulse oximetry plethysmographic waveform (POP) with partial pressure of end-tidal carbon dioxide (PETCO2) which could be used to reflect its quality in cardiopulmonary resuscitation (CPR), and then to determine the critical threshold of POP parameters in high quality CPR.
Study Overview
Status
Unknown
Conditions
Study Type
Observational
Enrollment (Anticipated)
1000
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
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Beijing, China, 100730
- Recruiting
- Peking Union Medical College Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 75 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
Patients who were admitted to the participant hospitals and met the inclusion criteria were included in the study.
Description
Inclusion Criteria:
- Cardiac arrested
- The time from cardiac arrest to receiving basic life support is less than 10 minutes
- Get advanced life support (endotracheal intubation and PETCO2 monitoring)
Exclusion Criteria:
- Defuse CPR
- chronic obstructive pulmonary disease (COPD) with type II respiratory failure
- Terminal malignant tumors or terminal stage of other diseases
- Rib fracture
- Cardiac arrest caused by hemorrhagic shock pulmonary embolism and cardiac tamponade
- Sever anemia(HGB<7g/dl)
- Untreated tension pneumothorax
- Tinea unguium, dyeing Fingernails and other factors affect the monitor of Pulse Oximetry Plethysmographic Waveform such vasculitis and Raynaud's phenomenon
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
the cut-off value of POP parameters in High Quality CPR
Time Frame: one year
|
Describe the the cut-off value of POP parameters in High Quality CPR.
Receiver operating curve analysis was performed to evaluate the accuracy in predicting return of spontaneous circulation (ROSC).
|
one year
|
Compare different predictors
Time Frame: one year
|
Area under curve (AUC) between potential predictors was compared by using a nonparametric test, and the optimal cutoff point was determined by estimating the Youden's index.
|
one year
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
September 1, 2015
Primary Completion (Actual)
June 30, 2018
Study Completion (Anticipated)
December 31, 2018
Study Registration Dates
First Submitted
November 15, 2018
First Submitted That Met QC Criteria
November 26, 2018
First Posted (Actual)
November 27, 2018
Study Record Updates
Last Update Posted (Actual)
November 27, 2018
Last Update Submitted That Met QC Criteria
November 26, 2018
Last Verified
November 1, 2018
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 201502019
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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