- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03989843
Impact of Embryo Cryopreservation on Birth Weight
June 19, 2019 updated by: University Hospital, Montpellier
Is Cryopreserved Embryo Replacement is Associated With Higher Birthweight Compared With Fresh Embryo ? Sibling Embryo Cohort Study
Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement.
No study has compared the BW of siblings conceived using the same oocyte/embryo cohort.
The aim of this study was to determine whether the freezing-thawing procedure is involved in such difference.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Actual)
183
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
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Montpellier, France, 34295
- UH Montpellier
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 43 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Sampling Method
Non-Probability Sample
Study Population
sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015.
Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study
Description
Inclusion Criteria:
- sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015.
Exclusion Criteria:
- Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Frozen embryo transfer
|
Fresh embryo transfer
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
birthweight
Time Frame: 1 day
|
change after FET than after fresh embryo transfer
|
1 day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Margaux Anav, Doctor, University Hospital, Montpellier
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 1, 2007
Primary Completion (Actual)
June 1, 2015
Study Completion (Actual)
June 30, 2015
Study Registration Dates
First Submitted
June 14, 2019
First Submitted That Met QC Criteria
June 14, 2019
First Posted (Actual)
June 18, 2019
Study Record Updates
Last Update Posted (Actual)
June 21, 2019
Last Update Submitted That Met QC Criteria
June 19, 2019
Last Verified
June 1, 2019
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- RECHMPL19_0306
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
IPD Plan Description
NC
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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