Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes (ESPRITO)

The goal if the project is to develop a learning health network devoted to the treatment of first episode psychosis.

Study Overview

• Status: Recruiting
• Conditions: First Episode Psychosis
• Intervention / Treatment: Other: Coordinated Specialty Care (CSC)

Detailed Description

The RAISE ETP study, designed and conducted by our group, signaled that a Coordinated Specialty Care (CSC) model could be feasibly delivered in community mental health clinics in multiple states and was effective. Since then, with the support of SAMSHA block grants to states, there are CSC programs across the nation.

The goal of this project is to develop a learning health system with sites providing CSC treatment of first-episode psychosis (FEP). Sites are drawn from five states: Connecticut, Florida, Michigan, Oklahoma and South Carolina. They vary in populations served, levels of funding available and research experience. All are committed to advancing the development of CSC using a health learning system model, to implementing a practical assessment strategy to enhance outcome assessment and to conducting research to improve outcomes that will be meaningful to the full range of stakeholders.

• Study Type: Observational
• Enrollment (Estimated): 700

Contacts and Locations

• Study Contact: Name: Patricia Marcy, BSN; Phone Number: 347-439-8035; Email: pmarcy@northwell.edu
• Study Contact Backup: Name: Cristina Gonzalez, MS; Phone Number: 347-804-3605

Study Locations

• United States
  • Florida
    • Lauderdale Lakes, Florida, United States, 33319
      • Recruiting
      • Henderson Behavioral Health
      • Contact: Suzelle Guinart

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years to 40 years (Child, Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

15 to 40 year olds with first episode psychosis enrolled in network CSC program

Description

Inclusion Criteria:

• Enrolled in CSC program

Exclusion Criteria:

• none

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of Enrolled participants	Number of enrolled participants into the learning health system	5 years of the project

Collaborators and Investigators

• Sponsor: Northwell Health
• Collaborators: National Institute of Mental Health (NIMH)

Study record dates

Study Major Dates

• Study Start (Actual): April 1, 2020
• Primary Completion (Estimated): July 27, 2024
• Study Completion (Estimated): July 27, 2024

Study Registration Dates

• First Submitted: June 28, 2019
• First Submitted That Met QC Criteria: June 28, 2019
• First Posted (Actual): July 2, 2019

Study Record Updates

• Last Update Posted (Actual): October 27, 2023
• Last Update Submitted That Met QC Criteria: October 26, 2023
• Last Verified: October 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Schizophrenia Spectrum and Other Psychotic Disorders; Schizophrenia
• Other Study ID Numbers: 19-0307

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No