Prevalence and Risk Factors for Common Diseases

Prevalence and Risk Factors for Common Diseases in Sweden: A Nationwide Cohort Study

By using national databases in Sweden the aim of the present project is to:

1. Investigate if the incidence of our most common diseases, such as fracture and cardiovascular disease, has changed from 1970-2017
2. To investigate whether the risk of death for our most common diseases have changed from 1970-2017.
3. To investigate the risk of a new episode after suffering from our most common diseases from 1970-2017
4. To investigate the risk factors for our most common diseases, and whether these have changed from 1970.
5. To investigate how severe disease or death affects the health of a close relative.

Study Overview

• Status: Unknown
• Conditions: Cardiovascular Diseases; Cancer; Fracture
• Intervention / Treatment: Other: To describe the incidence of disease and evaluate risk factors

Detailed Description

Please see above on the summary.

• Study Type: Observational
• Enrollment (Anticipated): 1000000

Contacts and Locations

• Study Contact: Name: Peter Nordström, Professor; Phone Number: +46907851000; Email: peter.nordstrom@umu.se
• Study Contact Backup: Name: Anna Nordström; Email: anna.h.nordstrom@umu.se

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Se above

Description

Inclusion Criteria:

• All people living in Sweden that is diagnosed with our most common diseases between 1970-2017.

Exclusion Criteria:

• None

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence of disease	To investigate the incidence of the most common diseases, and whether the incidence has changed.	1970-2017
Age at diagnosis of disease	To investigate age at diagnosis of our most common diseases, and whether this has changed.	1970-2017
Risk of death or disease in relative	Risk of death or disease in close relative to those diagnosed with severe disease or died.	1970-2017
Risk factors for disease or death	Risk factors for our most common diseases or death	1970-2017

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Risk for readmission	To investigate the risk of readmission for our most common diseases, and whether this risk has changed,	1970-2017

Collaborators and Investigators

• Sponsor: Anna Nordström
• Collaborators: Umeå University
• Investigators: Study Director: Peter Nordström, Professor, Umea University

Study record dates

Study Major Dates

• Study Start (Anticipated): November 1, 2019
• Primary Completion (Anticipated): November 1, 2020
• Study Completion (Anticipated): November 1, 2020

Study Registration Dates

• First Submitted: September 13, 2019
• First Submitted That Met QC Criteria: September 13, 2019
• First Posted (Actual): September 16, 2019

Study Record Updates

• Last Update Posted (Actual): October 8, 2019
• Last Update Submitted That Met QC Criteria: October 4, 2019
• Last Verified: September 1, 2019

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases
• Other Study ID Numbers: VasterbottenCounty

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No