Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Registry
January 12, 2026 updated by: The Lymphoma Academic Research Organisation
Anaplastic large cell lymphoma associated with breast implants (BIA-ALCL) is a rare disease seen only in women with a breast implant.
Because of the low incidence of this disease and the peculiar histological subtype, French authorities, in accordance with the recommendations of an expert group, recommended the implementation of a BIA-ALCL case registry, in connection with a national Multidisciplinary meeting (Réunion de Concertation Pluridisciplinaire nationale de recours- RCP).
This registry is opened in France and in Belgium
Study Overview
Status
Recruiting
Intervention / Treatment
Study Type
Observational
Enrollment (Estimated)
150
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Manon Croix
- Phone Number: +33 (04) 72 66 93 33
- Email: manon.croix.ext@lysarc.org
Study Locations
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Bruges, Belgium
- Recruiting
- A. Z. Sint-Jan Brugge-Oostende AV
-
Contact:
- Sylvia SNAUWAERT, MD
- Phone Number: +32 (0)50 45 23 28
- Email: sylvia.snauwaert@azsintjan.be
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Brussels, Belgium
- Recruiting
- Institut Jules Bordet
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Contact:
- Marie MAEREVOET, MD
- Phone Number: +32 2 541 31 11
- Email: marie.maerevoet@bordet.be
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Brussels, Belgium
- Not yet recruiting
- Universitair Ziekenhuis Brussel
-
Contact:
- Rik SCHOTS, MD
- Phone Number: 02 477 41 11
- Email: rik.schots@uzbrussel.be
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Brussels, Belgium
- Recruiting
- Clinique Universitaire Saint LUC
-
Contact:
- Nicole STRAETMANS, MD
- Phone Number: 02 764 18 00
- Email: nicole.straetmans@uclouvain.be
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Brussels, Belgium
- Not yet recruiting
- Cliniques Universitaires de Bruxelles - Hôpital Erasme
-
Contact:
- Virginie DE WILDE, MD
- Phone Number: +32 2 555 31 11
- Email: virginie.de.wilde@erasme.ulb.ac.be
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Edegem, Belgium
- Not yet recruiting
- Universitair Ziekenhuis Antwerpen
-
Contact:
- Wilfried SCHROYENS, MD
- Phone Number: +32 3 821 53 98
- Email: Wilfried.Schroyens@uza.be
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Ghent, Belgium
- Recruiting
- Universitair Ziekenhuis Gent
-
Contact:
- Fritz OFFNER, MD
- Phone Number: +32(0)92402138
- Email: fritz.offner@ugent.be
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Leuven, Belgium
- Recruiting
- U.Z. Leuven - Campus Gasthuisberg
-
Contact:
- Ann JANSSENS, MD
- Phone Number: +32 16 34 66 70
- Email: ann.janssens@uzleuven.be
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Liège, Belgium
- Recruiting
- CHU de Liège -Domaine Sart Tilman
-
Contact:
- Christophe BONNET, MD
- Phone Number: +32(0)43662851
- Email: cbonnet@ulg.ac.be
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Yvoir, Belgium
- Recruiting
- CHU UCL Namur - site Godinne
-
Contact:
- Marc ANDRE, MD
- Phone Number: 081/42 38 31
- Email: marc.andre@uclouvain.be
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Avignon, France
- Recruiting
- CH d Avignon - Hopital Henri Duffaut
-
Contact:
- Borhane SLAMA, MD
- Phone Number: 04 32 75 93 00
- Email: bslama@ch-avignon.fr
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Bordeaux, France
- Recruiting
- Institut Bergonie
-
Contact:
- Fontanet BIJOU, MD
- Phone Number: +33 05 56 33 78 32
- Email: f.bijou@bordeaux.unicancer.fr
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Brest, France
- Recruiting
- CHRU de Brest - Hopital Morvan
-
Contact:
- Adrian TEMPESCUL, MD
- Phone Number: 02 98 22 33 95
- Email: adrian.tempescul@chu-brest.fr
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Colmar, France
- Recruiting
- Hôpital Louis Pasteur
-
Contact:
- Bruno AUDHUY, MD
- Phone Number: 0389124104
- Email: bruno.audhuy@ch-colmar.rss.fr
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Créteil, France
- Recruiting
- APHP - Hopital Henri Mondor
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Contact:
- Corinne HAIOUN, MD
- Phone Number: 01 49 81 21 11
- Email: corinne.haioun@hmn.aphp.fr
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Dijon, France, 21034
- Recruiting
- CHU de Dijon - Hôpital le Bocage
-
Contact:
- Jean-Noel BASTIE, MD
- Phone Number: 03 80 29 50 41
- Email: jean-noel.bastie@chu-dijon.fr
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Lille, France
- Recruiting
- Centre Médical la Roseraie
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Contact:
- Manuel CLIQUENNOIS, MD
- Phone Number: 0320994055
- Email: cliquennois@maladiesdusang.fr
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Lyon, France
- Recruiting
- Centre Leon Berard
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Contact:
- Emmanuelle NICOLAS-VIRELIZIER, MD
- Phone Number: 04 78 78 28 28
- Email: emmanuelle.nicolas@lyon.unicancer.fr
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Marseille, France
- Recruiting
- Institut Paoli Calmettes
-
Contact:
- Jean Marc SCHIANO, MD
- Phone Number: 04 91 22 33 33
- Email: schianojm@ipc.unicancer.fr
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Montpellier, France
- Recruiting
- CH Saint-Eloi
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Contact:
- Guillaume CARTRON, MD
- Phone Number: +33(0)4 67 33 83 62
- Email: guillaume.cartron@orange.fr
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Nantes, France
- Recruiting
- CHU de Nantes - Hotel Dieu
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Contact:
- Béatrice MAHE, MD
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Paris, France
- Recruiting
- Hôpital Cochin
-
Contact:
- Bénédicte DEAU FISCHER, MD
- Phone Number: +33(0)158412132
- Email: benedicte.deau-fischer@cch.aphp.fr
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Pau, France
- Recruiting
- CH de Pau
-
Contact:
- Marcela ANITEI GHINEA, MD
- Phone Number: 05 59 72 67 96
- Email: marcela.anitei@ch-pau.fr
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Perpignan, France
- Recruiting
- CH de Perpigan
-
Contact:
- Laurence SANHES, MD
- Phone Number: 04 68 61 89 07
- Email: laurence.sanhes@ch-perpignan.fr
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Pierre-Bénite, France
- Recruiting
- Centre Hospitalier Lyon Sud
-
Contact:
- Gilles SALLES, MD
- Phone Number: 04 78 86 43 40
- Email: gilles.salles@chu-lyon.fr
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Reims, France
- Recruiting
- CHU de Reims - Hôpital Robert Debré
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Contact:
- Eric DUROT, MD
- Phone Number: +33(0)3 26 78 36 44
- Email: edurot@chu-reims.fr
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Rouen, France
- Recruiting
- Centre Henri Becquerel
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Contact:
- Fabrice JARDIN, MD
- Phone Number: +33 (0)2 32 08 29 09
- Email: fabrice.jardin@chb.unicancer.fr
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Saint-Cloud, France, 92210
- Recruiting
- Centre Rene Hugenin
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Contact:
- Sylvie GLAISNER, MD
- Phone Number: +33(0)1 47 11 15 15
- Email: sylvie.glaisner@curie.net
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St-Malo, France
- Recruiting
- CH de Saint Malo
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Contact:
- Claudia BIRLADEANU
- Phone Number: 02 99 21 21 50
- Email: C.BIRLADEANU@ch-stmalo.fr
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Strasbourg, France, 67100
- Recruiting
- CHRU de Strasbourg
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Contact:
- Elise TOUSSAINT, MD
- Phone Number: 03 88 11 67 28
- Email: elise.toussaint@chru-strasbourg.fr
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Toulouse, France
- Recruiting
- Institut Universitaire du Cancer - Oncopole Toulouse (IUCT-O)
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Contact:
- Lucie Oberic, Dr
- Phone Number: +33(0)561777666
- Email: oberic.l@chu-toulouse.fr
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
14 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Sampling Method
Non-Probability Sample
Study Population
Adult patients with an anaplastic large cell lymphoma associated with breast implants
Description
Inclusion Criteria:
- Adult patients with an anaplastic large cell lymphoma associated with breast implants
Exclusion Criteria:
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Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Other
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
BIA-ALCL
|
Observational : no intervention
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Overall response
Time Frame: 13 years
|
13 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
June 7, 2017
Primary Completion (Estimated)
June 7, 2032
Study Completion (Estimated)
June 7, 2032
Study Registration Dates
First Submitted
January 6, 2020
First Submitted That Met QC Criteria
January 6, 2020
First Posted (Actual)
January 7, 2020
Study Record Updates
Last Update Posted (Estimated)
January 14, 2026
Last Update Submitted That Met QC Criteria
January 12, 2026
Last Verified
January 1, 2026
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- BIA-ALCL Registry
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.