Predicting Intubation of Patients Hospitalised for Acutely Attacked Asthma

Predicting Factors of Intubation in Hospitalised Patients With Acutely Attacked Asthma

Although the asthmatic treatments currently be effective in term of efficacy of inhaled medications and good clinical outcome including symptom controlled and asthma exacerbation number, the large number of worse event still have been reported. Few cases eventually have been intubated and died even though using optimal medication. In this study, we will search to identify factors that may influence intubation in hospitalised patient with asthmatic attack.

Study Overview

• Status: Completed
• Conditions: Asthma; Intubation Complication

• Study Type: Observational
• Enrollment (Actual): 509

Contacts and Locations

Study Locations

• Thailand
  • Songkhla
    • Hat Yai, Songkhla, Thailand, 90110
      • Hatyai Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Population in this study is a the patient who had been admitted with moderate to severe asthmatic attack. The study will be retrospective review with data in medical record between year 2016-2018. The baseline characteristic and factors which has a potential to intubation will be recored.

Description

Inclusion Criteria:

• Patients who had been admitted and diagnosed as asthmatic attack between year 2016-2018.
• Patients who have age > 15 year old.

Exclusion Criteria:

• Non

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Intubated asthma attack; Patients who had been hospitalised with asthma attack, then intubated during hospitalisation.
Non-Intubated asthma attack; Patients who had been hospitalised with asthma attack without intubation during hospitalisation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number case of intubated patient	Number case of hospitalized asthmatic attack patients during 2-year review.	Retropectively review 2 years backard between 2017-2018

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of previous asthma attack before this admission	Number of previous asthma attack with 12 months before this hospitalization.	1 year before admission
Blood eosinophil count at admission time	Blood eosinophil may help predict outcome and risk for intubation.	Retropectively review 2 years backard between 2017-2018
Number patients dead	Number patient dead during hospitalization	Retropectively review 2 years backard between 2017-2018

Collaborators and Investigators

• Sponsor: Hat Yai Medical Education Center
• Investigators: Principal Investigator: Narongwit Nakwan, M.D., Hatyai Hospital

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2020
• Primary Completion (Actual): May 30, 2020
• Study Completion (Actual): May 30, 2020

Study Registration Dates

• First Submitted: February 15, 2020
• First Submitted That Met QC Criteria: February 18, 2020
• First Posted (Actual): February 20, 2020

Study Record Updates

• Last Update Posted (Actual): June 30, 2020
• Last Update Submitted That Met QC Criteria: June 28, 2020
• Last Verified: February 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Immune System Diseases; Lung Diseases; Hypersensitivity, Immediate; Bronchial Diseases; Lung Diseases, Obstructive; Respiratory Hypersensitivity; Hypersensitivity; Asthma
• Other Study ID Numbers: 65/2562

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No