Online Cognitive Behavioral Intervention Program for Hong Kong People With Depression (CANDO)

September 20, 2023 updated by: Jiayan Pan, Hong Kong Baptist University

Development of an Online Cognitive Behavioral Intervention Program to Reduce Depressive Symptoms for Hong Kong People With Depression

The purpose of this study is to develop a culturally and linguistically appropriate online cognitive behavioral intervention program-- with therapist guidance -- for Hong Kong Chinese adults suffering from major depressive disorder with mild to moderate depressive symptoms, and examine the effectiveness of this program in reducing their depressive symptoms and improving their mental health. The 3- and 6-month maintenance effect after 3 months and 6 months will also be tested.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Previous studies have demonstrated that online cognitive behavioral therapy can significantly reduce depressive symptoms and improve mental health for people with depression. This project will develop an online cognitive behavioral intervention program (including both an online platform and a smartphone application) for Hong Kong people with depression. Blended mode will be delivered service, which include 8-week online program, 2 face-to-face sessions and 2 telephone follow-ups by a clinical psychologist. The program will be evaluated in its effectiveness in reducing depressive and anxiety symptoms, psychological distress, negative thoughts and negative emotions and increasing positive thoughts and positive emotions.

Study Type

Interventional

Enrollment (Actual)

402

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Hong Kong resident
  • Has mild to moderate depressive symptoms
  • No suicidal risk in the past 3 months
  • Receive no face-to-face counselling since program commencement
  • Has access to a computer/smartphone with internet access
  • Has a valid email address

Exclusion criteria:

  • Has severe or no depressive symptoms
  • Has suicidal risk in the past 3 months
  • Currently receiving other psychological treatment
  • Suffer from severe psychiatric conditions, such as bipolar disorder or schizophrenia
  • Has no computer or smartphone with internet access
  • Has no valid email address

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: web-based cognitive behavioral intervention

The web-based program is consisted of 8 online modules, forum, internal messaging, reminder, online assessment and online booking. Each online module contains mood check, animation briefing and debriefing, case demonstration videos, session review and exercise.

Blended mode is adopted to deliver service, which includes the online program, two face-to-face session and 2 telephone follow-ups with a clinical psychologist.
Other: Confront and Navigate Depression Online (CANDO)
This study adopts a blended mode of service delivery, which included both online and offline intervention. The online intervention includes 8 weekly online model, animation briefing and debriefing, case demonstration video, exercise, forum, internal messaging, reminder, online assessment, session review and online booking system. The offline intervention includes two face-to-face sessions and two telephone follow-ups.
Experimental: app-based cognitive behavioral intervention

App-based cognitive behavioral intervention program The App-based program is consisted of 8 online modules, forum, internal messaging, reminder, online assessment and online booking. Each online module contains mood check, animation briefing and debriefing, case demonstration videos, session review and exercise.

Blended mode is adopted to deliver service, which includes the online program, two face-to-face session and 2 telephone follow-ups with a clinical psychologist
Other: Confront and Navigate Depression Online (CANDO)
This study adopts a blended mode of service delivery, which included both online and offline intervention. The online intervention includes 8 weekly online model, animation briefing and debriefing, case demonstration video, exercise, forum, internal messaging, reminder, online assessment, session review and online booking system. The offline intervention includes two face-to-face sessions and two telephone follow-ups.
No Intervention: Wait-list control group
No intervention will be provided when the experimental group is receiving services, but the access to the app-based program will be delivered to the wait-list control group after the two experimental groups complete the service.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Beck Depression Inventory-II (BDI-II)
Time Frame: 6 months
21-item rating scale for depressive symptoms
6 months
Patient Health Questionnaire-9 (PHQ-9)
Time Frame: 6 months
9-item rating scale for depressive symptoms.
6 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
General Health Questionnaire-12 (GHQ-12)
Time Frame: 6 months
12 item rating scale for psychological distress.
6 months
Beck Anxiety Inventory (BAI)
Time Frame: 6 months
21-item rating scale for symptoms of anxiety.
6 months
Chinese Automatic Thoughts Questionnaire (CATQ)
Time Frame: 6 months
20-item rating scale for automatic thoughts.
6 months
Chinese Affect Scale (CAS)
Time Frame: 6 months
20-item rating scale for positive and negative emotions of Chinese-speaking people.
6 months
Negative effects Questionnaire (NEQ) (administered at post-test only)
Time Frame: 6 months
20-item rating scale for negative effects caused by psychological treatment
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hong Kong Baptist University

Collaborators

Stockholm University
Richmond Fellowship of Hong Kong
Caritas Wellness Link - Tsuen Wan
Dr. Chiu Siu Ning
Innovation and Technology Fund for Better Living

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2019

Primary Completion (Actual)

June 30, 2022

Study Completion (Actual)

June 30, 2022

Study Registration Dates

First Submitted

May 12, 2020

First Submitted That Met QC Criteria

May 12, 2020

First Posted (Actual)

May 14, 2020

Study Record Updates

Last Update Posted (Actual)

September 22, 2023

Last Update Submitted That Met QC Criteria

September 20, 2023

Last Verified

September 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ITB/FBL/5002/18/P

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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