Effects of Exercise Intensity on Energy Intake, Appetite and Enjoyment in Overweight and Obese Females

Interval exercise involves short bouts of high intensity exercise interspersed with periods of lower intensity exercise. The benefit is that a shorter total duration of exercise may be required to achieve cardiovascular benefits similar to or even superior to traditional longer bouts of steady state endurance exercise. However how this type of exercise affects appetite and energy intake, particularly in overweight and obese females is not well known.

This study involves two trials of exercise, one at high intensity and one at low intensity, followed by a buffet lunch, in overweight and obese females.

Study Overview

• Status: Completed
• Conditions: Overweight and Obesity
• Intervention / Treatment: Other: Exercise

• Study Type: Interventional
• Enrollment (Actual): 11
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Pennsylvania
    • Scranton, Pennsylvania, United States, 18509
      • Human Physiology Lab

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

1. Female
2. Adult
3. apparently healthy
4. overweight or class I obese
5. eumenorrheic

Exclusion Criteria:

1. Diabetes
2. pregnancy
3. cardiovascular disease
4. greater than 1 hour of structured physical activity per week
5. thyroid disease
6. polycystic ovary disease

Study Plan

How is the study designed?

Design Details

• Primary Purpose: BASIC_SCIENCE
• Allocation: RANDOMIZED
• Interventional Model: CROSSOVER
• Masking: NONE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: high-intensity	Other: Exercise; high intensity exercise = 15 x 60 s sprints at 85% velocity of VO2max (vVO2max) with 60 s walking at 20% vVO2max or moderate intensity exercise = walking at 60% vVO2max
EXPERIMENTAL: low-intensity	Other: Exercise; high intensity exercise = 15 x 60 s sprints at 85% velocity of VO2max (vVO2max) with 60 s walking at 20% vVO2max or moderate intensity exercise = walking at 60% vVO2max

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in energy expenditure	caloric expenditure measured via indirect calorimetry	immediately pre-breakfast, immediately pre-exercise, during exercise, and immediately post-exercise.
Change in energy intake	measured via standardized lunch	immediately post exercise
Change in appetite	measured via circulating hormones leptin and acylated ghrelin	immediately pre-breakfast, immediately post-breakfast, immediately post-exercise and immediately pre-lunch
Change in subjective hunger	via visual analogue scale 100 mm, higher scores indicate greater hunger	baseline, immediately pre-exercise, immediately post-exercise, immediately pre-lunch, and immediately post-lunch

Collaborators and Investigators

• Sponsor: Ohio University
• Collaborators: Marywood University

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 1, 2016
• Primary Completion (ACTUAL): June 1, 2016
• Study Completion (ACTUAL): August 1, 2016

Study Registration Dates

• First Submitted: June 15, 2020
• First Submitted That Met QC Criteria: June 16, 2020
• First Posted (ACTUAL): June 18, 2020

Study Record Updates

• Last Update Posted (ACTUAL): June 18, 2020
• Last Update Submitted That Met QC Criteria: June 16, 2020
• Last Verified: June 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Body Weight; Overweight
• Other Study ID Numbers: 801776

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No