IJV Sonogram VS Cardiometry in Fluid Responsiveness In CABG
Internal Jugular Vein Sonogram Versus Electrical Cardiometry For Assessment Of Fluid Responsiveness In Adult Undergoing Coronary Artery Bypass Graft Surgery
The primary aim of the study is to assess the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using sonogram of the internal jugular vein for assessment of vessel distensibility in relation to stroke volume variation (SVV) measaured by electrical cardiometry.
The secondary aim is to evaluate the ability of thoracic fluid content (TFC) measured by electrical cardiometry to be an additive value for the assessment of fluid responsiveness.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Fluid management is one of the most important treatments for stabilizing hemodynamics in patients after cardiac surgery.Electrical Cardiometry is a method for the non-invasive determination of stroke volume (SV), cardiac output (CO), stroke volume variation (SVV) and other hemodynamic parameters in adults, children, and neonates based on measurement of thoracic electrical bioimpedance and has been validated against "gold standard" methods such as thermodilution method of deriving CO using a pulmonary artery catheter (PAC).
The IJV is, technically, much more easily accessible for sonographic visualization than the IVC, and measurement of the IJV does not require transesophageal echocardiography (TEE). Internal jugular vein distensibility index (IJVDI) has been studied in several studies but its reliability has not been well confirmed in patients during cardiac surgery.
This is a prospective observational study of adults undergoing coronary artery bypass graft surgery . The primary aim of the study is to assess the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using sonogram of the internal jugular vein for assessment of vessel distensibility in relation to stroke volume variation (SVV) measaured by electrical cardiometry.The secondary aim is to evaluate the ability of thoracic fluid content (TFC) measured by electrical cardiometry to be an additive value for the assessment of fluid responsiveness.
Volume responsiveness will be independently assessed by IJV sonogram and electrical cardiometry in following times
- After induction of anesthesia.
- After transfusing 6 ml / kg of hydroxyethyl starch (HES) 6% before sternotomy.
- After closure of the sternum and transfusion of patient's blood.
- Immediately before transferring the patient to ICU and stabilization of hemodynamic parameters by giving fluids needed to patient.
- Immediately after transferring the patient to ICU and stabilization of hemodynamic parameters by giving fluids needed to patient.
- After 2 hour of ICU admission.
- Before weaning from mechanical ventilation Fluid responsiveness will be assessed by examining SVV with a threshold of the SVV = 12% allow discrimination between Responders and Non-responders
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Alexandria, Egypt
- Alexandria University
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Demographic data, hemodynamic parameters as heart rate (HR), and mean arterial blood pressure (MAP),CVP and urine output have been registered.
Cardiac data derived from electrical cardiometry including: CO ,cardiac index( CI), stroke volume variation( SVV) and thoracic fluid content were also recorded.
IJVDI by sonogram was assessed
Description
Inclusion Criteria:
Adults (>18 years old) Able to provide advanced informed consent Planned for elective CABG surgery
Exclusion Criteria:
- Age < 18 years
- Severely reduced preoperative left ventricular ejection fraction < 40 %
- Significant cardiac arrhythmia.
- Significant valvular heart disease.
- Clinically evident pulmonary disease.
- Bilaterally inserted venous catheters (jugular or subclavian vein)
- History of radiotherapy or surgery of the neck region.
- Inability to obtain interpretable ultrasound images due to a difficult acoustic window.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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fluid responsiveness after fluid challenge
Time Frame: 24 hours from the start of surgery
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Correlation between SVV and IJVDI
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24 hours from the start of surgery
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Collaborators and Investigators
Publications and helpful links
General Publications
- Aronson S, Nisbet P, Bunke M. Fluid resuscitation practices in cardiac surgery patients in the USA: a survey of health care providers. Perioper Med (Lond). 2017 Oct 19;6:15. doi: 10.1186/s13741-017-0071-6. eCollection 2017.
- Ma GG, Hao GW, Yang XM, Zhu DM, Liu L, Liu H, Tu GW, Luo Z. Internal jugular vein variability predicts fluid responsiveness in cardiac surgical patients with mechanical ventilation. Ann Intensive Care. 2018 Jan 16;8(1):6. doi: 10.1186/s13613-017-0347-5.
Study record dates
Study Major Dates
Study Start (ACTUAL)
Primary Completion (ACTUAL)
Study Completion (ACTUAL)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ACTUAL)
Study Record Updates
Last Update Posted (ACTUAL)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- IJVDI and fluid responsiveness
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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