Post- Rotatory Nystagmus Test: Normative Data for Spanish Adolescents and Adults

Normative Data for Post-rotatory Nystagmus Test at Spanish Adolescent and Adult Population: a Transversal Study

The vestibulo-ocular reflex is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address.

Study Overview

• Status: Not yet recruiting
• Conditions: Vestibular Function Tests; Nystagmus Vestibular
• Intervention / Treatment: Diagnostic test: Post-rotatory nystagmus test

Detailed Description

The vestibulo-ocular reflex (VOR) is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. This system has an important role in our balance, stabilization of the visual field when our head moves, awareness of the position of our head in space, postural control and functions of the Autonomous Nervous System.

The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address. This article aims to explore the use of the PRN test for adolescent and adults, to prove if the duration of the VOR is longer in these population than in children. It will be also recollected personal data to study whether exposure to vestibular input influences its reactivity and perception.

• Study Type: Observational
• Enrollment (Anticipated): 163

Contacts and Locations

• Study Contact: Name: Vico Rocío; Phone Number: +34 658144741; Email: rociovicoquesada@gmail.com
• Study Contact Backup: Name: Pedrero Yolanda; Phone Number: + 34 697355054; Email: yolandapedmar@hotmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 13 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

People over 13 years, that lives in the north, middle and south of Spain, and meet the selection criteria.

Description

Inclusion Criteria:

• People over 13 years of age.
• Spanish-speaking population.
• Signature of the informed consent.

Exclusion Criteria:

• Diagnosis of a neurodevelopmental or neurological disorder.
• Being in occupational therapeutic treatment for balance or vestibular problems.
• Practice of sports in one previous hour.
• Adverse reaction to vestibular input such as vomiting, discoloration, feeling of unpleasantness or any other type of negative reaction before / during / after the administration of the NPR.

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Crossover
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Duration of vestibular-ocular reflex after the administration of nystagmus post-rotatory test in adolescent and adult population	The post rotatory nystagmus test evaluates the duration of the vestibular-ocular reflex: how long its lats gives information about the perception of vestibular system. This reflex reflects the role of the vestibular system in ocular mechanisms (Mailloux et al., 2014). It is administered twice: clockwise and counterclockwise.After the administration the physiologic nystagmus appears, it is our vestibular-ocular reflex, and the examiner has to register the duration of it.	End of the nystagmus post rotatory test and end of the vestibular-ocular reflex

Collaborators and Investigators

• Sponsor: Quesada, Rocío Vico
• Investigators: Principal Investigator: Vico Rocío, Quesada, Rocío Vico; Principal Investigator: Pedrero Yolanda, Quesada, Rocío Vico; Principal Investigator: Zisa Nerina, Quesada, Rocío Vico

Publications and helpful links

General Publications

• Mailloux Z, Leao M, Becerra TA, Mori AB, Soechting E, Roley SS, Buss N, Cermak SA. Modification of the postrotary nystagmus test for evaluating young children. Am J Occup Ther. 2014 Sep-Oct;68(5):514-21. doi: 10.5014/ajot.2014.011031.

Study record dates

Study Major Dates

• Study Start (Anticipated): April 1, 2021
• Primary Completion (Anticipated): June 1, 2021
• Study Completion (Anticipated): September 1, 2021

Study Registration Dates

• First Submitted: March 4, 2021
• First Submitted That Met QC Criteria: March 8, 2021
• First Posted (Actual): March 9, 2021

Study Record Updates

• Last Update Posted (Actual): March 9, 2021
• Last Update Submitted That Met QC Criteria: March 8, 2021
• Last Verified: March 1, 2021

More Information

Terms related to this study

• Keywords: adult; adolescent; vestibular function tests; nystagmus, physiologic
• Additional Relevant MeSH Terms: Nervous System Diseases; Eye Diseases; Cranial Nerve Diseases; Ocular Motility Disorders; Nystagmus, Pathologic
• Other Study ID Numbers: 010395

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No