Isolated Pancreatic Loop With Modified Pancreaticojejunostomy

Modified Pancreaticojejunostomy Technique With Isolated Pancreatic Loop After Pancreaticoduodenectomy Reduces Postoperative Pancreatic Fistula: a Retrospective Study

The aim of the present study was to observe whether the modified pancreatico- jejunostomy (PJ ) technique with an isolated pancreatic loop would effectively reduce the POPF rate and overall morbidity after PD

Study Overview

• Status: Completed
• Conditions: Pancreaticoduodenectomy
• Intervention / Treatment: Procedure: duodenopancreatectomy

Detailed Description

Postoperative pancreatic fistula (POPF) is widely regarded as the most threatening complication following pancreaticoduodenectomy (PD). Its clinical impact and sequelae have been previously described and shown to contribute to the development of other morbid complications and high rates of mortality.

The aim of the present study was to observe whether the modified pancreatico- jejunostomy (PJ ) technique with an isolated pancreatic loop would effectively reduce the POPF rate and overall morbidity after PD.

Methods: We report our early experience using a modified PJ technique with an isolated pancreatic loop after after PD in 201 patients between January 2010 and December 2020.

• Study Type: Observational
• Enrollment (Actual): 201

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years to 70 years (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

all patients undergoing duodenopancreatectomy procedure, in the surgery department .

Description

Inclusion Criteria:

• age up to 30
• head of the pancreas tumor

Exclusion Criteria:

• body and tail pancreatic tumors

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
patients operated for pancreas tumors; duodenopancreatectomy for head of the pancreas tumors	Procedure: duodenopancreatectomy; resection of the head of the pancreas, the mower part of the biliary duct, and antrectomy

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
incidence of pancreatic fistula	level of lipase in abdominal drain after suregry	10 years

Collaborators and Investigators

• Sponsor: Université de Sousse
• Investigators: Study Director: ali ben ali, PROFESSOR, university of sousse

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2010
• Primary Completion (Actual): December 31, 2020
• Study Completion (Actual): December 31, 2020

Study Registration Dates

• First Submitted: April 7, 2021
• First Submitted That Met QC Criteria: April 11, 2021
• First Posted (Actual): April 13, 2021

Study Record Updates

• Last Update Posted (Actual): April 13, 2021
• Last Update Submitted That Met QC Criteria: April 11, 2021
• Last Verified: April 1, 2021

More Information

Terms related to this study

• Keywords: Pancreaticoduodenectomy; pancreaticojejunostomy; Postoperative pancreatic fistula.
• Additional Relevant MeSH Terms: Digestive System Diseases; Pathological Conditions, Anatomical; Pancreatic Diseases; Digestive System Fistula; Fistula; Pancreatic Fistula
• Other Study ID Numbers: U23471

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No