Clinical Anatomy of Superficial Veins of Lower Limbs

The study is focused on clinical anatomy of superficial veins of lower limbs. We are mapping their anatomy via ultrasonography. We are focusing on saphenopopliteal junction and communicants between small saphenous vein and great saphenous vein.

Study Overview

• Status: Active, not recruiting
• Conditions: Saphenous Vein Injury
• Intervention / Treatment: Other: No intervention

Detailed Description

Research project is focused on superficial veins of lower extremities, especially their clinical anatomy. Superficial veins are located within the compartimentum saphenum. The function of superficial veins is drainage of intradermal and epifascial spaces. Superficial veins and their function are fundamental in development of chronic venous disorder. These veins are physiologically connected with deep venous system via perforators but also between each other via communicanting veins. Communicanting veins between small saphenous vein and great saphenous vein have not been described yet, particularly because of their variations. Clinically important is also the saphenopopliteal junction in the fossa poplitea. This region features many variations, which were described in many studies. Also, the nomenclature of saphenopopliteal juction is not standardised in comparison to the saphenofemoral junction. Moreover, many articles are pointing out that there were not specified all potential drainage ways of the cranial extension of small saphenous vein (extesio cranialis). Articles are uniform neither in its prevalence nor in its terminology.

The knowledge of connections between the superficial and deep venous systems as well as knowledge of communicanting veins between superficial veins is important for diagnosis and proper treatment of chronic venous disorder. Variabilities of these veins can play fundamental role in choosing the proper graft for aorto-coronary bypass grafting. The ununiformed nomenclature of superficial veins, their communicating veins and junctions can cause misleading preoperative diagnosis and overlooking of these structures in clinical practise.

• Study Type: Observational
• Enrollment (Anticipated): 400

Contacts and Locations

Study Locations

• Czechia
  • Prague, Czechia, 12200
    • First faculty of medicine, Charles University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

European population

Description

Inclusion Criteria:

• women and men
• age 18-80

Exclusion Criteria:

• wounds on lower limbs

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
healthy volunteers; Healthy volunteers with no sign of internal disease. Age 18-50, both women and men.	Other: No intervention; this is an observational study
patients with internal disease; Patients with internal disease, both women and men.	Other: No intervention; this is an observational study

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The Anatomy of superficial Veins of Lower Limbs	the anatomy observed by ultrasonography imaging focus on communicans between small saphenous vein and great saphenous vein	2022-2024

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The Anatomy of Superficial Veins of Lower Limbs: junction saphenopopliteal	clinical anatomy of saphenopopliteal junction and its variations observed by ultrasound imaging	2022-2024

Collaborators and Investigators

• Sponsor: Charles University, Czech Republic
• Investigators: Principal Investigator: Michaela Hronová, doctor, 1. faculty of Medicine, Charles University

Study record dates

Study Major Dates

• Study Start (ACTUAL): November 1, 2021
• Primary Completion (ACTUAL): October 30, 2022
• Study Completion (ANTICIPATED): August 1, 2023

Study Registration Dates

• First Submitted: October 18, 2021
• First Submitted That Met QC Criteria: October 18, 2021
• First Posted (ACTUAL): October 29, 2021

Study Record Updates

• Last Update Posted (ACTUAL): February 13, 2023
• Last Update Submitted That Met QC Criteria: February 9, 2023
• Last Verified: February 1, 2023

More Information

Terms related to this study

• Keywords: great saphenous vein; small saphenous vein; saphenopopliteal junction; venae intersaphenae
• Other Study ID Numbers: CHU185797621

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No