The Study of Regional Lung Ventilation-perfusion by EIT

October 24, 2021 updated by: Peking Union Medical College Hospital
This is a prospective observational trial. The purpose of this study is to explore the feasibility of EIT monitoring pulmonary blood flow and the consistency and difference between EIT monitoring pulmonary local ventilation blood flow and SPECT and CTPA monitoring methods

Study Overview

Status

Recruiting

Conditions

Study Type

Observational

Enrollment (Anticipated)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • China
    • Beijing
      • Beijing, Beijing, China
        • Recruiting
        • Peking Union Medical College Hospital
        • Contact:
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Patients who need CTPA examination in the Department of nuclear medicine / radiology of Peking Union Medical College Hospital

Description

Inclusion Criteria:

  1. Admission to ICU was less than 72 hours;
  2. Age ≥ 18 years old and ≤ 80 years old;
  3. Volunteer to participate after communicating with patients' family members;

Exclusion Criteria:

  1. The patients with heart implants could not be monitored by EIT;
  2. Patients or their families refused to participate in the study;
  3. Hypernatremia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
EIT group
patients went through EIT detection
CTPA group
patients went through CTPA detection

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Regional pulmonary perfusion by EIT
Time Frame: 1 Day
Using EIT to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio
1 Day
Regional pulmonary perfusion by CTPA
Time Frame: 1 Day
Using CTPA to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio
1 Day

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Regional pulmonary ventilation index by EIT
Time Frame: 1 Day
Regional pulmonary ventilation index by EIT, including GI: global inhomogeneity CoV: center of ventilation, ROI: region of interest
1 Day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Peking Union Medical College Hospital

Investigators

  • Study Director: Yun Long, Peking Union Medical College Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2020

Primary Completion (Anticipated)

June 1, 2023

Study Completion (Anticipated)

June 1, 2023

Study Registration Dates

First Submitted

January 28, 2021

First Submitted That Met QC Criteria

October 24, 2021

First Posted (Actual)

November 3, 2021

Study Record Updates

Last Update Posted (Actual)

November 3, 2021

Last Update Submitted That Met QC Criteria

October 24, 2021

Last Verified

October 1, 2021

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • PUMCH-EIT-PE

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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