Impact of eHealth Education to Reduce Anemia Among School-going Adolescent Girls in Rural Bangladesh

February 26, 2024 updated by: Md Jiaur Rahman, Hiroshima University

Anemia Prevalence, Associated Factors, and Impact of eHealth Education Among School-going Adolescent Girls in Rural Bangladesh

Adolescent girls are the highly vulnerable group to develop anemia due to reproductive immaturities, poor personal hygiene, lack of nutritional intake, and lack of health education in the rural area of Bangladesh. Rapid advantage of technology, eHealth is the promising tool to overcome the barriers and provide appropriate health guidelines in distant rural communities by developing knowledge, attitude, and practice to reduce anemia and mitigate risk among the school-going adolescent girls. This research aims (1) To evaluate eHealth education's impact on reducing anemia among adolescent girls in rural Bangladesh. (2) To assess the effect of eHealth education to change the knowledge, attitude, and practice among adolescent girls regarding anemia. A Randomized Control Trial study will be conducted from May 22, 2022, to January 21, 2023, in the two schools at the Chandpur district, Bangladesh. During the 8th months' intervention, will be provided eHealth education by the trained community health worker. The participant will be allocated who will be diagnosed as anemic through the blood hemoglobin screening. The sample size was calculated, and the total sample is 138. In this study, one school will be considered an intervention group and another school control group through the simple coin toss randomization technique. Then random sampling technique will be used to select study participants.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Globally 1.62 billion people affect anemia, a significant public health threat, especially in low and middle-income countries (LMICs). The prevalence of anemia among non-pregnant and school-going is 30% and 25%, respectively, and 35% of this anemia in the LMICs. Anemia is a medical condition that can develop at any life stage, but at the reproductive age of women, adolescent girls (10-19 years), and growing children are susceptible. Adolescent age is a critical period of developmental transmission and reproductive maturation, requiring increased nutritional intake and proper health education; otherwise, it leads adolescents more vulnerable to future development. The primary reasons for developing anemia are the lack of iron-containing food intake, contaminated water, and poor sanitation. Also, the infection with soil-transmitted helminth is one of the leading blood losses causes of anemia.

Bangladesh is a middle-income, highly populated developing country. As per World Health Organization (WHO) 2019 data, Bangladesh has a 36.7% anemia prevalence among women of reproductive age. According to the WHO, if anemia prevalence is more than 40%, it is an alarming and severe public health problem. The whole-population anemia prevalence satisfies the criteria apparently; however, focusing on sub-population, it does not. For example, among the non-pregnant women's anemia, 73% live in rural Bangladesh. A scientific article reported that 51.6% of adolescent girls were suffering from anemia; 46%, 5.4%, and 0.2% were mild, moderate, severe anemia, respectively. Due to the high prevalence of rural women and adolescent girls' anemia in Bangladesh, adolescents are the highly venerable and more focused group. The lack of education, shortage of iron intake, poor economic status, poor personal hygiene, unhygienic toilets, parasitic infection are the main risk factors of anemia in Bangladesh. Proper interventions, including health education, should be provided to those vulnerable populations. i.e., adolescent girls in rural areas.

Lifestyle and behavioral change depend on knowledge, and nutritional knowledge is essential for good dietary habits. Health education is an effective way to increase knowledge. A school-based nutritional education reported that it is a feasible tool improving the hemoglobin level, knowledge, attitudes, and practices among adolescents. Health education is a useful approach to creating awareness among adolescent girls to reduce preventable diseases like anemia and build a future healthy mother.

In Bangladesh, mobile phone (85%) and network (99%) coverage are high among the rural communities, which is effective in delivering health education through eHealth technology. eHealth is the cost-effective and secure use of information and communications technologies supporting health and health-related fields, including health-care services, health surveillance, health literature, and health education, knowledge, and research (WHO E-Health Resolution 2005). mHealth is an important part of eHealth, which is the use of mobile and wireless technologies to support the achievement of health objectives and is viewed as having the potential to transform the face of health service delivery.

To investigators' knowledge, specific research is lacking about the effect of eHealth education among adolescent girls to create awareness and knowledge about the preventive, control, and risk reduction strategies of anemia in the school-going adolescent girls of rural Bangladesh. Moreover, knowledge gaps still exist regarding food habits and dietary practice, hygiene maintenance, lifestyle and behavior, medication adherence, etc., which are important factors developing anemia.

Knowledge gap:

To investigators' knowledge, specific research is lacking about the effect of eHealth education among adolescent girls to create awareness and knowledge about the preventive, control, and risk reduction strategies of anemia in the school-going adolescent girls of rural Bangladesh. Moreover, knowledge gaps still exist regarding food habits and dietary practice, hygiene maintenance, lifestyle and behavior, medication adherence, etc., which are important factors developing anemia.

Study Type

Interventional

Enrollment (Actual)

138

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Bangladesh
      • Chandpur, Bangladesh, 3603
        • Baburhat high school and Zubaida girl school

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

10 years to 19 years (Child, Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. Who is diagnosed with mild and moderate anemia in the baseline screening of the study.
  2. Who gives written consent to participate in the study through the legal guardian/participants.
  3. Who is living and studying Chandpur district with assigned school for the study.

Exclusion Criteria:

  1. Participants whose guardians/participants do not have a mobile phone will be excluded from the study.
  2. Who is pregnant will be excluded from our study.
  3. Who are physically and mentally sick will be excluded from our study.

3. Disagree to participate in this study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Intervention Group
  1. Two surveys: Demographic, lifestyle, hygiene-related (1) & knowledge, attitude, and practice (2) regarding anemia at baseline and end line of study.
  2. Investigations and physical examination will perform for CBC blood test except ESR, urine R/E, stool R/E, Height, weight for BMI, waist circumference, hip circumference, hip - waist ratio, and mid-upper arm circumference (MUAC) at baseline, mid-line, and end-line of study.
Behavioral: eHealth education

eHealth education intervention regarding the dietary plan, healthy-lifestyle, and hygiene:

  1. Group-wise eHealth education through online PowerPoint presentation session among study participants with their guardian: Two times (Before starting the intervention and mid-line; end of 4th-month intervention)

  2. eHealth education through phone calls & SMS

    • 1st to 4th month: 4 times in a month
    • 5th to 6th month: 3 times in a month
    • 6th to 8th month: 2 times in a month
  3. Control group will not get care and education
No Intervention: Control Group
  1. Two surveys: Demographic, lifestyle, hygiene-related (1) & knowledge, attitude, and practice (2) regarding anemia at baseline and end line of study.
  2. Investigations and physical examination will perform for CBC blood test except ESR, urine R/E, stool R/E, Height, weight for BMI, waist circumference, hip circumference, hip - waist ratio, and mid-upper arm circumference (MUAC) at baseline, mid-line, and end-line of study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Impact of eHealth education to change the anemia level among school-going adolescent girls in rural areas of Bangladesh
Time Frame: 8 months after intervention
Individuals school-going adolescent girls will be measured anemia level (No anemic, mild, moderate, and severe anemia) through the blood hemoglobin screening by the auto-hematology analyzer. According to WHO, 10-11 years adolescent girls Hb <11.5g/dl will be considered anemic, and <10-11.4, 7.0-9.9 g/dl, <7.0 g/dl will be considered mild, moderate, and severe anemia, respectively. Non-pregnant adolescent girls (12-19 years) Hb level < 12 g/dl will be considered suffering any form of anemia, and 10.0-11.9 g/dl, 7.0-9.9 g/dl, and <7.0 g/dl will be considered mild, moderate, and severe anemia, respectively. After eHealth education intervention, changes will be assessed (e.g., anemic to non-anemic, severe to mild/ moderate/non-anemic, moderate to mild/non-anemic, mild to non-anemic) from the baseline of anemia level among the school-going adolescent girls.
8 months after intervention

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Changes of knowledge, attitude, and practice regarding anemia among the school-going adolescent girls in rural areas of Bangladesh
Time Frame: 8 months after intervention
The impact of eHealth education in changing knowledge, attitude, and practice regarding anemia will be assessed among school-going adolescent girls. Knowledge, attitude, and practice (KAP) will be measured through an adapted KAP model questionnaire of the Food and Agriculture Organization (FAO) at baseline and end of eight months of study. The questionnaire consisted of the multiple-choice options 'Yes', 'No,' and 'I don't know'. Correct responses will be given a score of 1, and incorrect responses will be given a score of 0. The option 'I don't know' will be considered as lack of knowledge and given a score of 0. KAP scores will be calculated by adding the number of correct answers divided by the total number of questions and multiplying by 100 to obtain a percentage score.
8 months after intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hiroshima University

Collaborators

North South University, Bangladesh

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 22, 2022

Primary Completion (Actual)

February 1, 2023

Study Completion (Actual)

January 30, 2024

Study Registration Dates

First Submitted

December 4, 2021

First Submitted That Met QC Criteria

December 22, 2021

First Posted (Actual)

January 11, 2022

Study Record Updates

Last Update Posted (Actual)

February 28, 2024

Last Update Submitted That Met QC Criteria

February 26, 2024

Last Verified

February 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2021/OR-NSU/IRB/1102

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Subscribe