Exercise Intensity for Down Syndrome Children

Effect of Exercise Intensity on Knee and Ankle Joints' Torque and Functional Mobility in Children With Down's Syndrome: a Randomized Controlled Trial

The current study aimed to determine the appropriate exercise intensity for the rehabilitation of children with down syndrome.

Study Overview

• Status: Completed
• Conditions: Down Syndrome
• Intervention / Treatment: Other: treadmill exercise (mild); Other: treadmill exercise (moderate)

Detailed Description

Two groups of down syndrome children were recruited. one group received mild-intensity treadmill training while the other received moderate-intensity treadmill training. Eccentric knee extensors and ankle plantar flexors peak torques were assessed before and after the intervention. Also, functional mobility was assessed for both groups before and after the intervention. The within and between-subjects effect was used to analyze the obtained data before and after the intervention. isokinetic dynamometer and the time up and go test were used for evaluation.

• Study Type: Interventional
• Enrollment (Actual): 34
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Saudi Arabia
  • Mecca
    • Ta'if, Mecca, Saudi Arabia, 2425
      • College of Applied Medical Sciemces

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 8 years to 12 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• independent walking
• Intelligence quotient range from 40 to 70
• right dominant foot
• body mass index from 50 to 75

Exclusion Criteria:

• chronic diseases
• congenital anomalies
• involved in any competitive sport
• previous injury to the lower limb

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: mild intensity group; Received mild intensity treadmill training according to Martti Karvonen's formula.	Other: treadmill exercise (mild); mild intensity treadmill training.
Experimental: moderate intensity group; Received moderate intensity treadmill training according to Martti Karvonen's formula.	Other: treadmill exercise (moderate); moderate-intensity treadmill training

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
knee extensor peak torque	eccentric normalized peak torque of the knee extensors of the dominant limb.	three months
ankle plantar fexors peak torque	eccentric normalized peak torque of the ankle plantar flexors of the dominant limb.	three months
functional mobility	the assessment of the time up and go test	three months

Collaborators and Investigators

• Sponsor: Taif University
• Investigators: Principal Investigator: Hatem H Allam, ass. prof., Taif University

Study record dates

Study Major Dates

• Study Start (Actual): December 10, 2019
• Primary Completion (Actual): March 15, 2020
• Study Completion (Actual): March 27, 2020

Study Registration Dates

• First Submitted: February 26, 2022
• First Submitted That Met QC Criteria: February 26, 2022
• First Posted (Actual): March 8, 2022

Study Record Updates

• Last Update Posted (Actual): March 8, 2022
• Last Update Submitted That Met QC Criteria: February 26, 2022
• Last Verified: February 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Disease; Congenital Abnormalities; Genetic Diseases, Inborn; Intellectual Disability; Abnormalities, Multiple; Chromosome Disorders; Syndrome; Down Syndrome
• Other Study ID Numbers: 291

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No