Acute Exercise Type and Cognitive Function: An Event-related Potential Study

April 1, 2022 updated by: Yi-Ting Cheng, National Taiwan Normal University

Effects of Different Types of Acute Exercise on Cognitive Function: An Event-related Potential Study

This study aims to examine the effects of different types of acute exercise on cognitive functions in healthy adults.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Acute exercise, a single session of exercise, has been shown to enhance cognitive functions. The meta-analysis research has suggested that such benefits might depend upon the types of exercise. However, the predominant types of exercise examined within this area of research are aerobic and resistance exercises. The effects of other types of exercises on cognitive functions are poorly understood. Accordingly, this study is going to examine the effects of different types of acute exercise [i.e., aerobic exercise (AE), aerobic exercise with virtual reality (AE-VR), and combined exercise (CE)] on cognitive functions.

140-180 healthy young adults will be recruited and then randomly assigned to the AE, AE-VR, CE, and Control groups for a 35-minute intervention. Cardiovascular fitness will be assessed beforehand. Additionally, Stroop tasks and several questionnaires will be conducted before and after the intervention. The targeted primary outcomes are changes in cognitive behavior performance (assessed by the Stroop tasks) and neuroelectrical indices (e.g., P3 of event-related potential). The secondary outcomes are the changes in exercise enjoyment, motivation, and emotion.

Study Type

Interventional

Enrollment (Anticipated)

160

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taipei, Taiwan, 106
        • Recruiting
        • Department of Physical Education and Sport Sciences, National Taiwan Normal University
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 30 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • no major psychiatric illness or physical disease
  • able to do 30-minutes moderate exercise
  • normal or corrected-to-normal vision
  • right-handed
  • moderate exercise ≤ 150 min/week

Exclusion Criteria:

  • any neurological, respiratory, vascular, metabolic, or brain-relative disease
  • any physical limitation or injury
  • any wounds on the scalp
  • have experience of using technology products
  • regular engagement in exercise training programs

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: aerobic exercise group (AE)
35-min cycling at moderate intensity (50-60% heart rate reserve).
Behavioral: aerobic exercise group (AE)
The participants will ride the cycle ergometer for 35 minutes. The training consisted of a 5-minute warm-up period followed by 25 minutes of moderate exercise and a 5-minute recovery.
Experimental: aerobic exercise with virtual reality group (AE-VR)
35-min cycling at moderate intensity (50-60% heart rate reserve) with 3D virtual reality.
Behavioral: aerobic exercise with virtual reality group (AE-VR)
The participants will receive the 3D VR training program and ride the cycle ergometer at the same time. The training protocol is similar to the aerobic exercise group.
Experimental: combined exercise group (CE)
This 35-min exercise combines aerobic, bodyweight exercise, and meditation.
Behavioral: combined exercise group (CE)
The intervention consists of 5-minutes aerobic warm-up, 25-minutes bodyweight exercise, and 5-minutes mindfulness meditation for recovery. The participants will follow the video to do the program.
Active Comparator: control group
It has a 35-minute video about exercise science.
Behavioral: Control group
Participants will watch a 35-min video about exercise science.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Inhibition performance: Changes in Stroop test performance
Time Frame: 30 minutes each at the pretest and posttest
The computerized Stroop test will be administrated to assess participants' cognitive functions, and their changes in reaction time and accuracy will be examined.
30 minutes each at the pretest and posttest
Changes in neuroelectrical activities
Time Frame: 30 minutes each at the pretest and posttest
The neuroelectrical activities during the computerized cognitive tasks will be recorded. The changes in the event-related potential (e.g., P3) will be analyzed.
30 minutes each at the pretest and posttest

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Changes in physical activity enjoyment
Time Frame: 5-10 minutes each at the pretest and posttest
The Chinese version of the physical activity enjoyment scale (PACES) questionnaire, with a total of 13 items, will be used to examine the changes in physical activity enjoyment. Participants will rate "how you feel at the moment about the exercise you have been doing" using a 7- point bipolar Likert scale, from 1 (I enjoy it) to 7 (I hate it).
5-10 minutes each at the pretest and posttest
Changes in motivation
Time Frame: 3-5 minutes each at the pretest and posttest
The Chinese version of the Motivation for Future Use questionnaire will be used. The scale consists of 3 items and each item is scored on a Likert-type scale that ranges from 1 to 7, with higher scores indicating a higher level of motivation.
3-5 minutes each at the pretest and posttest
Changes in emotion
Time Frame: 5-10 minutes each at the pretest and posttest
The Chinese version of the positive and negative affect schedule (PANAS) will be used to assess the changes in emotion levels. It is a self-reporting questionnaire consisting of two 10-item scales and each item is scored on a Likert-type scale that ranges from 1 (not at all) to 5 (very much).
5-10 minutes each at the pretest and posttest

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan Normal University

Investigators

  • Principal Investigator: Yu-Kai Chang, Department of Physical Education and Sport Sciences, National Taiwan Normal University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 20, 2022

Primary Completion (Anticipated)

March 1, 2023

Study Completion (Anticipated)

March 1, 2023

Study Registration Dates

First Submitted

March 15, 2022

First Submitted That Met QC Criteria

March 15, 2022

First Posted (Actual)

March 24, 2022

Study Record Updates

Last Update Posted (Actual)

April 4, 2022

Last Update Submitted That Met QC Criteria

April 1, 2022

Last Verified

April 1, 2022

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • PACNL_1100301_YTTY

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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