Extensively Diseased Left Anterior Descending Coronary Artery: On Pump vs Off Pump CABG?

June 28, 2022 updated by: Kareem Ahmed Hosny, Assiut University
Diseased left Anterior descending coronary artery (LAD) is one of the most challenging conditions in Bypass surgery. we investigate whether on-pump coronary artery bypass grafting (CABG) is more beneficial in those critical patients or off-pump surgery.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

100

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Assiut, Egypt, 2112
        • Recruiting
        • Assiut university heart hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

30 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • any patient with diffuse LAD disease indicated for open heart surgery

Exclusion Criteria:

  • no concomitant valve disease
  • any patient can be treated by medical treatment or PCI

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Case
Patients with extensive LAD disease treated with off-pump CABG
Procedure: Off-Pump CABG
coronary artery grafting by beating heart technique
Other: Control
Patients with extensive LAD disease treated with on-pump CABG
Procedure: On-Pump CABG
coronary artery grafting by using cardiopulmonary bypass machine
Other Names:
  • CABG

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
mortality
Time Frame: 30 days post operative
follow up post-operative track of the patient for any noticed mortality rate
30 days post operative
Morbidity
Time Frame: 60 days post operative
follow up post-operative track of the patient for any noticed complications
60 days post operative

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 25, 2022

Primary Completion (Anticipated)

February 24, 2023

Study Completion (Anticipated)

March 1, 2023

Study Registration Dates

First Submitted

February 26, 2022

First Submitted That Met QC Criteria

June 28, 2022

First Posted (Actual)

July 5, 2022

Study Record Updates

Last Update Posted (Actual)

July 5, 2022

Last Update Submitted That Met QC Criteria

June 28, 2022

Last Verified

June 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AssiutMed

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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