Effects of Different Anesthesia on Odor Memory

August 11, 2022 updated by: Gamze Küçükosman, Zonguldak Bulent Ecevit University

Comparison of the Effects of TIVA and Inhalation Anesthesia Methods on Olfactory Functions and Olfactory Memory

This study aimed to research the effect of different general anesthesia administration on postoperative smell functions and memory.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

97

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Zonguldak, Turkey, 67600
        • Gamze Küçükosman

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 60 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

97

Description

Inclusion Criteria:

  • American Society of Anesthesiologists (ASA) I-II risk groups
  • operated under elective conditions with general anesthesia requiring intubation
  • operation durations of 40-180 minutes.

Exclusion Criteria:

  • intracranial,
  • endocrine or nasal surgery,
  • pregnant cases,
  • those with history of respiratory tract diseases and psychiatric disease, with disorder of odor reception and perception,
  • with smoking and chronic alcohol use,
  • requiring a nasogastric probe

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Group P (n=40) (Propofol),
Diagnostic test: butanol threshold test and smell identification tests
no additional intervention
Group PS (n=40) (Propofol-Sevoflurane),
Diagnostic test: butanol threshold test and smell identification tests
no additional intervention
Group S (n=40) (Sevoflurane).
Diagnostic test: butanol threshold test and smell identification tests
no additional intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Butanol Threshold Test
Time Frame: during 24 hour after surgery
threshold detection and odor discrimination
during 24 hour after surgery
Odor Identification Test
Time Frame: during 24 hour after surgery
odor discrimination
during 24 hour after surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zonguldak Bulent Ecevit University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2013

Primary Completion (Actual)

June 30, 2013

Study Completion (Actual)

July 1, 2013

Study Registration Dates

First Submitted

June 2, 2022

First Submitted That Met QC Criteria

August 11, 2022

First Posted (Actual)

August 12, 2022

Study Record Updates

Last Update Posted (Actual)

August 12, 2022

Last Update Submitted That Met QC Criteria

August 11, 2022

Last Verified

August 1, 2022

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 2013/02

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Smell Functions

Clinical Trials on butanol threshold test and smell identification tests

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Peru

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe