Effect of Various Intensities of tDCS on Dual Task Cognitive Functions in Normal Subjects

Effect of Various Intensities of tDCS on Dual Task Cognitive Functions in Normal Subjects: A Pilot Study

Transcranial Direct Current Stimulation (tDCS) is a neuroregulatory method that delivers a weak straight tendency to neuronal areas with the intention of changing the brain's basic metabolic processes. Degradation of executive performance may not necessarily arise from cathodal stimulation, and vice versa for anodal stimulation.

Study Overview

• Status: Recruiting
• Conditions: Cognitive Functions
• Intervention / Treatment: Device: tDCS

Detailed Description

Total 48 samples were taken, were randomly allocated into an experimental group of 4 variance of different intensities of tDCS. At F3 and F4, tDCS was applied to the desired region. Electrodes were put in using the 10-20 EEG technique throughout the parietal cortex, with the current electrode being set on F3 area and control electrode being positioned on the F4 area. For 20 minutes over three days per week for up to three weeks, current intensities of 0.5mA for group A, 1.0mA for group B, 1.5mA for group C, and 2.0mA for group D were administered. when engaging in dual-task cognitive processes. The groups are going to receive 9 sessions of tDCS treatment. The MoCA and TMT scale was completed by samples before and after the intervention. Finally, specifics investigation will be carried out using SPSS 26.0 software.

• Study Type: Interventional
• Enrollment (Estimated): 48
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Elina Osik, BPT; Phone Number: 7629956147; Email: elinaosik18@gmail.com
• Study Contact Backup: Name: Elina Osik, BPT; Phone Number: 7629956147; Email: elinaosik@gmail.com

Study Locations

• India
  • Haryana
    • Ambala, Haryana, India, 133207
      • Recruiting
      • MMIPR
      • Contact: Subhashish Chatterjee, MPT(NEURO); Phone Number: +918950037407; Email: subhasishphysio@gmail.com
      • Principal Investigator: Subhashish Chatterjee, MPT

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Physically healthy students only
• Willing to participate in the study

Exclusion Criteria:

• Any recent trauma or injury on the head of subjects
• If contact with the scalp is not possible
• Any resonant implant close to electrode placement site

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

Experimental: Intensities of tDCS and dual task cognitive functions; We have done in a one arm type. The participants are divided into different intensity group (0.5 mA, 1.0 mA, 1.5 mA and 2.0 mA).

Device: tDCS; 4 variance of different intensities of tDCS (0.5mA, 1 mA, 1.5mA and 2mA). At F3 and F4, tDCS was applied to the desired region. Electrodes were put in using the 10-20 EEG technique throughout the parietal cortex, with the current electrode being set on F3 area and control electrode being positioned on the F4 area. For 20 minutes over three days per week for up to three weeks, current intensities of 0.5mA for group A, 1.0mA for group B, 1.5mA for group C, and 2.0mA for group D were administered. when engaging in dual-task cognitive processes. The groups are going to receive 9 sessions of tDCS treatment.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
MoCA	A quick test for minor cognitive impairment. It evaluates a variety of cognitive processes, including executive functioning, recall, speech and direction. The assessment has 30 points and requires 10 mins to finish for each person. A typical result is that 26 and more is normal.	10 mins

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
TRAIL MAKING TEST	TMT part A includes 25 rounds containing the digits 1 to 25 scribbled haphazardly within every round on a sheet of paper. TMT part B similarly includes 25 rounds on a sheet of paper, but this rounds includes digits (1-12) and alphabet (A-L) instead of only being digits.	3 minutes

Collaborators and Investigators

• Sponsor: Maharishi Markendeswar University (Deemed to be University)
• Investigators: Principal Investigator: Subhashish Chatterjee, MPT(NEURO), Maharishi Markendeshwar Institute of Physiotherapy and Rehabilitation, Ambala, Haryana, 133207

Study record dates

Study Major Dates

• Study Start (Actual): August 1, 2023
• Primary Completion (Estimated): February 10, 2024
• Study Completion (Estimated): March 10, 2024

Study Registration Dates

• First Submitted: February 2, 2024
• First Submitted That Met QC Criteria: February 2, 2024
• First Posted (Actual): February 9, 2024

Study Record Updates

• Last Update Posted (Actual): February 9, 2024
• Last Update Submitted That Met QC Criteria: February 2, 2024
• Last Verified: February 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: SPC-PA-07

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No