The Findings of Magnetic Resonance Imaging in Subtypes of Tics-related Disorders

August 5, 2024 updated by: National Taiwan University Hospital

The Findings of Resting-state Functional Magnetic Resonance Imaging, Diffusion Spectrum Imaging, and Wideband Magnetic Resonance Imaging in Subtypes of Tics-related Disorders

The findings of resting-state functional magnetic resonance imaging and diffusion spectrum imaging in subtypes of tics-related disorders

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Taiwan
      • Taipei, Taiwan, 100
        • Recruiting
        • National Taiwan University Children Hospital Pediatric Neurology Department
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

3 years to 14 years (Child, Adult)

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

We enrolled treatment-naive Tourette syndrome or chronic tic disorder pediatric patients for Tourette group and healthy age- and gender-matched participants for healthy control

Description

Inclusion Criteria:

  • Age less than 18 years old
  • Diagnosed as Tourette syndrome or chronic tic disorders

Exclusion Criteria:

  • History of neuropsychiatric disorders
  • Already receive treatment for Tourette syndrome/chronic tics disorder
  • Have some device not allowed for MRI scan

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Crossover
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Tourette
Age less than 18 years old Diagnosed as Tourette syndrome or chronic tic disorders No other neuropsychiatric disorders
Diagnostic test: Brain MRI
All participants receive brain MRI evaluation and clinical evaluation of tic severity.
Healthy
Age less than 18 years old No other neuropsychiatric disorders
Diagnostic test: Brain MRI
All participants receive brain MRI evaluation and clinical evaluation of tic severity.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Difference between healthy and Tourette group
Time Frame: 2 years after enrollment for primary evaluation
Difference of MRI result between healthy and Tourette group
2 years after enrollment for primary evaluation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Investigators

  • Principal Investigator: Wang-Tso Lee, National Taiwan University Children Hospital Pediatric Neurology Department

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 20, 2015

Primary Completion (Estimated)

August 1, 2025

Study Completion (Estimated)

December 1, 2030

Study Registration Dates

First Submitted

September 30, 2022

First Submitted That Met QC Criteria

September 30, 2022

First Posted (Actual)

October 4, 2022

Study Record Updates

Last Update Posted (Actual)

August 6, 2024

Last Update Submitted That Met QC Criteria

August 5, 2024

Last Verified

August 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 201503062RIND

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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