Relationship Between Isometric Muscle Strength and Gross Motor Function in Children With Unilateral Cerebral Palsy

Muscle strength can be defined as the ability of skeletal muscle to develop force for the purpose of providing stability and mobility within the musculoskeletal system, so that functional movement can take place.

Study Overview

• Status: Completed
• Conditions: Cerebral Palsy; Hemiplegia
• Intervention / Treatment: Other: correlation

Detailed Description

Cerebral palsy describes a group of disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fatal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, cognition, communication, perception, and/or behaviour, and/or by a seizure disorder

The development and changes in motor function, both natural and with therapy, can be assessed using the Gross Motor Function Measure (GMFM) created for children with CP

• Study Type: Observational
• Enrollment (Actual): 97

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt, 002
    • Badr University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 2 years to 8 years (Child)
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Muscle weakness was found in children with CP, increasing with severity of gross motor function, approximately 50% of the predicted muscle strength was needed to be able to walk without aids.

Description

Inclusion Criteria:

1. Their age between 6 and 12 years old.
2. Grade 1and 2 according to the Modified Ashworth scale (RW and Smith, 1987).
3. They could walk with limitation or holding on according to GMFCS (level I, II) (Palisano et al., 1997).
4. They were able to understand and follow verbal instructions.

Exclusion Criteria:

1. Children with any visual or auditory problems.
2. Children with any surgical interference in the lower limb.
3. Children with any structural deformities in joints and bones of lower limbs.
4. Children with any special medications affecting muscle functions (anti-spastic drugs).
5. Children who suffer from other diseases or associated disorders that interfered with physical activity.

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Gross motor function measure	standing and walking domain	3 months
Isometric muscle strength	a handheld dynamometer	3 months

Collaborators and Investigators

• Sponsor: Badr University
• Investigators: Principal Investigator: Omnya samy, PHD, Lecturer

Study record dates

Study Major Dates

• Study Start (Actual): November 7, 2022
• Primary Completion (Actual): January 12, 2023
• Study Completion (Actual): February 12, 2023

Study Registration Dates

• First Submitted: November 5, 2022
• First Submitted That Met QC Criteria: November 5, 2022
• First Posted (Actual): November 14, 2022

Study Record Updates

• Last Update Posted (Actual): April 11, 2023
• Last Update Submitted That Met QC Criteria: April 8, 2023
• Last Verified: April 1, 2023

More Information

Terms related to this study

• Keywords: Cerebral Palsy; Hemiplegia; muscle stength; gmfm
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Brain Damage, Chronic; Cerebral Palsy; Paralysis; Hemiplegia
• Other Study ID Numbers: Omnya3

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: private

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No