Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort

August 31, 2025 updated by: Yu Bo

Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort - a Prospective, Multicenter Study

AMI Survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" (project number 2016YFC1301100) and completed the 1-year visit were followed up by telephone at 3 years (within the corresponding follow-up time window) and 5 years after discharge to acquire the patients' medication, health status, and major adverse cardiovascular and cerebrovascular events, including death, heart failure, rehospitalization, re-myocardial infarction, revascularization, stroke, malignant arrhythmia, and bleeding events.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

15000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • China
    • Beijing Municipality
      • Beijing, Beijing Municipality, China
      • Beijing, Beijing Municipality, China, 100029
        • Recruiting
        • Beijing An Zhen Hospital, Capital Medical University
        • Contact:
      • Beijing, Beijing Municipality, China
        • Recruiting
        • Beijing Chao-Yang Hospital, Capital Medical University
        • Contact:
    • Guangdong
      • Guangzhou, Guangdong, China
        • Recruiting
        • Guangdong General Hospital
        • Contact:
          • Ning Tan
    • Guangxi
      • Nanning, Guangxi, China, 530021
        • Recruiting
        • The First Affiliated Hospital of Guangxi Medical University
        • Contact:
          • Lang Li
    • Hebei
      • Shijiazhuang, Hebei, China
        • Recruiting
        • Second Hospital of Hebei Medical University
        • Contact:
    • Heilongjiang
      • Daqing, Heilongjiang, China
    • Henan
      • Zhengzhou, Henan, China
        • Recruiting
        • The First Affiliated Hospital of Zhengzhou University
        • Contact:
          • Zhe Meng
          • Phone Number: +8618137793359
    • Jiangsu
      • Nanjing, Jiangsu, China, 210009
        • Recruiting
        • Zhongda Hospital Southeast University
        • Contact:
          • Genshan Ma
    • Jiangxi
      • Nanchang, Jiangxi, China, 330006
        • Recruiting
        • The Second Affiliated Hospital of Nanchang University
        • Contact:
          • Yanqing Wu
    • Jilin
      • Changchun, Jilin, China, 150056
        • Recruiting
        • The Second Hospital of Jilin University
        • Contact:
        • Principal Investigator:
          • Bin Liu, MD, PhD
    • Liaoning
      • Dalian, Liaoning, China
        • Recruiting
        • The econd Affiliated Hospital of Dalian Medical University
        • Contact:
          • Peng Qu
      • Shenyang, Liaoning, China
        • Recruiting
        • General Hospital of Northern Theater Command of the Chinese People's Liberation Army
        • Contact:
          • Bin Wang
          • Phone Number: +8615309882359
        • Principal Investigator:
          • Bin Wang
    • Shanxi
      • Xi’an, Shanxi, China
        • Recruiting
        • Xijing Hospital of Air Force Military Medical University
        • Contact:
    • Sichuan
      • Chongqing, Sichuan, China, 400000
        • Recruiting
        • Xinqiao Hospital Army Medical University
        • Contact:
        • Principal Investigator:
          • Zhexue Qin, MD,PhD
    • Tianjin Municipality
      • Tianjin, Tianjin Municipality, China
        • Recruiting
        • The General Hospital of Tianjin Medical University
        • Contact:
      • Tianjin, Tianjin Municipality, China
        • Recruiting
        • Tianjin Chest Hospital
        • Contact:
          • Chunjie Li
        • Principal Investigator:
          • Yin Liu
        • Principal Investigator:
          • Chunjie Li
        • Principal Investigator:
          • Mei Ma
    • Xinjiang
      • Ürümqi, Xinjiang, China
        • Recruiting
        • First Affiliated Hospital of Xinjiang Medical University
        • Contact:
          • Xiang Ma
          • Phone Number: +8613669939349

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

AMI survivors who participated in the project "Construction and key technology research on the whole myocardial protection system for acute myocardial infarction" and completed 1-year visit

Description

Inclusion Criteria:

  • AMI survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" and completed the 1-year visit.
  • Telephone to obtain informed consent from the subjects/family members of the subjects.

Exclusion Criteria:

  • Not available

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
optimized group
the patients received at least one optimized treatment
Other: Treatment Strategies
AMI emergency treatment process, pre-reperfusion medication, reperfusion strategy selection, and early cardiac rehabilitation after reperfusion
un-optimized group
the patients didn't receive optimized treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Incidence of MACCE
Time Frame: 5 years after discharge
the incidence of MACCE (death, heart failure, rehospitalization, re-myocardial infarction, re-myocardial revascularization, stroke, malignant arrhythmia, bleeding events, etc.) in AMI patients
5 years after discharge

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Differences of MACCE between the optimized group and the non-optimized group
Time Frame: 5 years after discharge
Differences of the MACCE between the optimized group and the non-optimized group
5 years after discharge
Differences of the MACCE between OCT-guided group and the coronary angiography -guided group
Time Frame: 5 years after discharge
Differences of the MACCE between OCT-guided group and the coronary angiography -guided group
5 years after discharge
Differences of MACCE between defer PCI group and direct PCI group
Time Frame: 3 and 5 years after discharge
Differences of MACCE between defer PCI group and direct PCI group
3 and 5 years after discharge
Differences of the MACCE incidence between cardiac rehabilitation quality improvement group and non-cardiac rehabilitation group
Time Frame: 5 years after discharge
Differences of the MACCE incidence between cardiac rehabilitation quality improvement group and non-cardiac rehabilitation group
5 years after discharge

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Yu Bo

Investigators

  • Study Chair: Bo Yu, The Second Affiliated Hospital of Harbin Medical University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 21, 2022

Primary Completion (Estimated)

August 30, 2025

Study Completion (Estimated)

December 30, 2026

Study Registration Dates

First Submitted

May 8, 2023

First Submitted That Met QC Criteria

May 8, 2023

First Posted (Actual)

May 17, 2023

Study Record Updates

Last Update Posted (Estimated)

September 3, 2025

Last Update Submitted That Met QC Criteria

August 31, 2025

Last Verified

August 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KY2022-266

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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