A Multicenter Observational Cohort of Degenerative Spine Diseases in China（DSDC） (DSDC)

A Multicenter Observational Cohort of Degenerative Spine Diseases in China

Study type: The objectives of this observational study were to understand, analyze, and compare the treatment and prognosis of patients with degenerative spine diseases and to construct a risk warning model and an assisted decision-making system

The main questions it aims to answer are:

• [question 1] to construct a database of patients with degenerative spinal diseases and to study their associated prognosis, complications, and other risks
• [Question 2] Use big data to build a risk early warning model and assisted decision making system The study will not intervene with patients

Study Overview

• Status: Completed
• Conditions: Degenerative Spine Diseases

• Study Type: Observational
• Enrollment (Actual): 10000

Contacts and Locations

Study Locations

• China
  • Xianmen, China, 361102
    • Wenle Li

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients with degenerative spine disease (lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis, scoliosis deformity, etc.) seen and treated in participating units between January 2015 and January 2022, excluding patients with neoplastic disease

Description

Inclusion criteria:

• patients with degenerative spine disease admitted to the units participating in the study from January 2015 to mid-January 2022;
• complete patient data with no more than 5% missing;

Exclusion Criteria:

• Patients with oncology;

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Collect demographics (Hospital Information System)	Collect demographics from the HIS system for patients with degenerative spine disease	2022.03

Collaborators and Investigators

• Sponsor: Xiamen University
• Investigators: Principal Investigator: Wenle Wenle, M.D., Xiamen University

Study record dates

Study Major Dates

• Study Start (Actual): March 1, 2022
• Primary Completion (Actual): March 10, 2022
• Study Completion (Actual): March 1, 2023

Study Registration Dates

• First Submitted: May 11, 2023
• First Submitted That Met QC Criteria: May 19, 2023
• First Posted (Actual): May 22, 2023

Study Record Updates

• Last Update Posted (Actual): May 22, 2023
• Last Update Submitted That Met QC Criteria: May 19, 2023
• Last Verified: May 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Bone Diseases; Spinal Diseases
• Other Study ID Numbers: XiamenUDSDC

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No