Cardiac Response to Strength Training in Hypertensive Individuals

September 9, 2025 updated by: Antonio Roberto Zamunér, Universidad Católica del Maule

Evaluation of Cardiac Response to High and Low-Intensity Strength Training in Hypertensive Subjects

This study aims to determine the acute effects of high and low-intensity strength training on cardiac autonomic control in hypertensive subjects

Study Overview

Status

Completed

Detailed Description

The present study aims to determine the cardiovascular response in hypertensive individuals between 30 and 60 years old to one session of high and low intensity strength training.

Participants will undergo a low-intensity strength training including squats, barbell rows, deadlifts and chest presses with a load dynamic of 12 repetitions for 6 sets at an execution speed of less than 55 % of your maximum weight. This is followed by a one-week washout period. Subsequently, high intensity strength training is performed with the same exercises but with a load of 6 repetitions for 6 series at an intensity greater than 80% of the maximum repetition speed. The order of the sessions will be random.

After each session, blood pressure will be recorded for 24 hours using a holter monitor, which will report pressures during both day and night

The results obtained will be determined by the differences in the before and after values. Consequently, the behavior of the following variables: 1) heart rate variability, 2) blood pressure and 3) heart rate will determine the final results of this research.

The entire study will be carried out at the Catholic University of Maule, in its Kinesiology laboratory.

Study Type

Interventional

Enrollment (Actual)

28

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Maule Region
      • Talca, Maule Region, Chile, 3469001
        • Universidad Católica del Maule

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Participants exclusively diagnosed with hypertension by a medical professional

Exclusion Criteria:

  • Participants with any other chronic medical condition
  • Subjects with any upper or lower limb injury that prevents strength training
  • Subjects with cardiovascular abnormalities other than hypertension

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: high intensity
The low-intensity group undergoes a strength training program using barbells, weights and dumbbells consisting of 6 sets of 6 repetitions each, with an execution speed equal to or greater than 80% of the maximum velocity used in the one-repetition maximum
High intensity group: participants will be requested to perform the following exercises: 1)squat, 2)rowing, 3)deadlift and 4)bench press. All exercises will be performed with high intensity (80% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.
Experimental: Low Intensity
The low-intensity group undergoes a strength training program using barbells, weights and dumbbells, consisting of 6 sets of 12 repetitions each, with an execution speed below 40% of the maximum velocity used in the one-repetition maximum
Low intensity group: participants will be requested to perform the following exercises: 1)squat, 2) rowing, 3)deadlift and 4)bench press. All exercises will be performed with low intensity (40% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Heart rate variability
Time Frame: 2 hours
Determine the effects of high and low-intensity strength training on heart rate variability, based on the time between each heartbeat, during the assessment
2 hours
Blood pressure systolic
Time Frame: 24 hours
Determine the effects of high and low intensity resistance training on blood pressure with a blood pressure monitor for 24 hours.
24 hours
Blood pressure diastolic
Time Frame: 24 hours
Determine the effects of high and low intensity resistance training on blood pressure diastolic with a blood pressure monitor for 24 hours.
24 hours
Blood pressure mean
Time Frame: 24 hours
Determine the effects of high and low intensity resistance training on blood pressure mean with a blood pressure monitor for 24 hours.
24 hours
Heart Rate
Time Frame: 24 hours
Determine the effects of high and low intensity strength training on the behavior of heart rate, using a heart rate monitor, throughout the intervention.
24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 20, 2023

Primary Completion (Actual)

July 20, 2024

Study Completion (Actual)

July 20, 2024

Study Registration Dates

First Submitted

April 12, 2024

First Submitted That Met QC Criteria

April 12, 2024

First Posted (Actual)

April 17, 2024

Study Record Updates

Last Update Posted (Estimated)

September 16, 2025

Last Update Submitted That Met QC Criteria

September 9, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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