- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06483126
The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease
Study Overview
Status
Conditions
Detailed Description
To participate in this online study, you will need an email address, and a smartphone or laptop/desktop with internet access. If you are eligible to participate, you will be sent a link to an online survey (Qualtrics). We will ask questions about demographic and health information, followed by questions about exercise habits, exposure to natural environments (including greenspaces and bluespaces, among others), and questionnaires assessing mood, motivation, cognition, sleep, stress, quality of life, and related functions. The survey should take roughly 20-25 minutes to complete. This is an observational study only, and not an interventional study.
Compensation: A $15 Amazon gift card will be offered to those who complete the survey all the way through with good effort.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Massachusetts
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Boston, Massachusetts, United States, 02215
- Vision and Cognition Laboratory, Boston University
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
For persons with Parkinson's disease:
- Participants must be at least 40 years old
- Have a diagnosis of idiopathic PD
- Be proficient English speakers
- Have functional vision
- Have internet access, and access to a smartphone/laptop/desktop
For persons without Parkinson's disease:
- Participants must be healthy middle-aged and older adults, with no diagnosis of neurological/neurodegenerative conditions
- Participants must be at least 40 years old
- Be proficient English speakers
- Have functional vision
- Have internet access, and access to a smartphone/laptop/desktop
Exclusion Criteria (both groups):
- Diagnosis of dementia
- Poor vision (non-functional range)
- Lack of access to internet or to a smartphone/ laptop/desktop computer.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Persons with Parkinson's disease (PwPD)
Individuals with a diagnosis of Parkinson's disease
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Persons without Parkinson's disease
Healthy middle-aged and older adults
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Parkinson's Disease Sleep Scale-2
Time Frame: Baseline
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Assesses sleep and nocturnal disturbances in Parkinson's disease.
Maximum score: 60.
Higher scores indicate more frequent sleep disturbances.
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Baseline
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Parkinson's Anxiety Scale (PAS)
Time Frame: Baseline
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Assesses the severity of anxiety symptoms in persons with Parkinson's disease.
Maximum score:48.
Higher scores indicate more severe anxiety.
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Baseline
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NIH NeuroQoL measures
Time Frame: Baseline
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Assesses health-related quality of life in adults with neurological disorders.
Higher scores on the sub-scales indicate worse outcomes.
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Baseline
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Nature Connection Index
Time Frame: Baseline
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Assesses the extent to which people feel connected to nature.
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Baseline
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Perceived Restorativeness Scale
Time Frame: Baseline
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Assesses the extent to which particular environments have restorative qualities.
Higher scores indicate greater perceived restorativeness.
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Baseline
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Center for Epidemiological Studies Depression (CES-D)
Time Frame: Baseline
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Assesses depressive symptoms in the general population.
Maximum score:60.
Higher scores indicate more severe depression.
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Baseline
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Perceived Stress Scale
Time Frame: Baseline
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Assesses how different situations affect feelings and perception of stress.
Maximum score: 40.
Higher scores indicate higher perceived stress.
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Baseline
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Parkinson's Disease Questionnaire - 8 (PDQ-8)
Time Frame: Baseline
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Assesses Parkinson's disease-specific health-related quality of life.
Maximum Score: 32.
Higher scores indicate worse quality of life.
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Baseline
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Collaborators and Investigators
Investigators
- Principal Investigator: Alice Cronin-Golomb, PhD, Boston University
Publications and helpful links
General Publications
- Alcock I, White MP, Wheeler BW, Fleming LE, Depledge MH. Longitudinal effects on mental health of moving to greener and less green urban areas. Environ Sci Technol. 2014 Jan 21;48(2):1247-55. doi: 10.1021/es403688w. Epub 2014 Jan 7.
- Gascon M, Triguero-Mas M, Martinez D, Dadvand P, Forns J, Plasencia A, Nieuwenhuijsen MJ. Mental health benefits of long-term exposure to residential green and blue spaces: a systematic review. Int J Environ Res Public Health. 2015 Apr 22;12(4):4354-79. doi: 10.3390/ijerph120404354.
- Hartig T, Mitchell R, de Vries S, Frumkin H. Nature and health. Annu Rev Public Health. 2014;35:207-28. doi: 10.1146/annurev-publhealth-032013-182443. Epub 2014 Jan 2.
- Rigolon A, Browning MHEM, McAnirlin O, Yoon HV. Green Space and Health Equity: A Systematic Review on the Potential of Green Space to Reduce Health Disparities. Int J Environ Res Public Health. 2021 Mar 4;18(5):2563. doi: 10.3390/ijerph18052563.
- Rodriguez-Loureiro L, Casas L, Bauwelinck M, Lefebvre W, Vanpoucke C, Vanroelen C, Gadeyne S. Social inequalities in the associations between urban green spaces, self-perceived health and mortality in Brussels: Results from a census-based cohort study. Health Place. 2021 Jul;70:102603. doi: 10.1016/j.healthplace.2021.102603. Epub 2021 Jun 21.
- Cerin E, Barnett A, Shaw JE, Martino E, Knibbs LD, Tham R, Wheeler AJ, Anstey KJ. From urban neighbourhood environments to cognitive health: a cross-sectional analysis of the role of physical activity and sedentary behaviours. BMC Public Health. 2021 Dec 23;21(1):2320. doi: 10.1186/s12889-021-12375-3.
- Cerin E, Barnett A, Shaw JE, Martino E, Knibbs LD, Tham R, Wheeler AJ, Anstey KJ. Urban Neighbourhood Environments, Cardiometabolic Health and Cognitive Function: A National Cross-Sectional Study of Middle-Aged and Older Adults in Australia. Toxics. 2022 Jan 7;10(1):23. doi: 10.3390/toxics10010023.
- Miller IN, Neargarder S, Risi MM, Cronin-Golomb A. Frontal and posterior subtypes of neuropsychological deficit in Parkinson's disease. Behav Neurosci. 2013 Apr;127(2):175-183. doi: 10.1037/a0031357. Epub 2013 Feb 11.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Estimated)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 7175E
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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