The Difference of Weight Gain Tendencies and Obesity During Pregnancy

The Difference of Weight Gain Tendencies During Pregnancy According to Pregestational Body Mass Indices of the Mothers in Two Different Ethnic Populations- Does it Make Difference Regarding Neonatal Outcomes?

Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia, stillbirth, and neonatal death. These risks vary by maternal age, race, and ethnicity, with rising rates among immigrant and minority women. This study investigates overweight and obesity rates in pregnant women, weight gain during pregnancy, and adherence to guidelines and possible neonatal outcomes, comparing Turkish and Syrian immigrant women.

Methods: This retrospective single-center study was conducted at Buca Seyfi Demirsoy Teaching and Research Hospital in Izmir, Turkey, over one year. Data collected included demographic information, pregnancy complications, delivery modes, maternal and neonatal anthropometric measurements, and neonatal morbidity and mortality. The study included Turkish and Syrian women with complete medical records. Statistical analyses were performed using SPSS software, with significance set at p < 0.05.

Study Overview

• Status: Completed
• Conditions: Birth Weight; Obesity, Maternal; Weight Gain, Maternal; Birth Outcome, Adverse
• Intervention / Treatment: Other: No intervention

Detailed Description

Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia, stillbirth, and neonatal death. These risks vary by maternal age, race, and ethnicity, with rising rates among immigrant and minority women. This study investigates overweight and obesity rates in pregnant women, weight gain during pregnancy, and adherence to guidelines and possible neonatal outcomes, comparing Turkish and Syrian immigrant women.

Methods: This retrospective single-center study was conducted at Buca Seyfi Demirsoy Teaching and Research Hospital in Izmir, Turkey, over one year. Data collected included demographic information, pregnancy complications, delivery modes, maternal and neonatal anthropometric measurements, and neonatal morbidity and mortality. The study included Turkish and Syrian women with complete medical records. Statistical analyses were performed using SPSS software, with significance set at p < 0.05.

• Study Type: Observational
• Enrollment (Actual): 323

Contacts and Locations

Study Locations

• Turkey
  • Izmir, Turkey
    • Buca Seyfi Demirsoy RTH

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

In the study, the hospital records of all pregnant women admitted for delivery at the obstetrics ward of the Women's and Children's Diseases additional service building Buca Seyfi Demirsoy Training and Research Hospital were retrospectively reviewed over a 6-month period from September 1, 2022, to February 28, 2023.

Description

Inclusion Criteria:

• Being admitted to our hospital for delivery or having just given birth
• Being Turkish or Syrian
• Having all detailed information, including mothers' pregestational and immediate pre-delivery body weights, available in medical records

Exclusion Criteria:

• Significant deficiencies in medical records
• Belonging to an ethnic group other than Turkish or Syrian

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Turkish; Belonging to Turkish race originally	Other: No intervention; No intervention is made, groups are formed just due to the races.
Syrian; Belonging to Syrian race originally	Other: No intervention; No intervention is made, groups are formed just due to the races.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Maternal weight gain	Total body weight gained by pregnant women during pregnancy according to the measurements made by "Tanita" scale	1 year period until inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Obesity and overweight	Pregestational obesity or being overweight	6 months

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Neonatal morbidities	Neonatal morbidities experienced by the babies	6 months
Adherence to the weight gain guidelines	Adherence to the recommendations of current guidelines regarding total body weight gain according to the measurements made by "Tanita" scale	6 months

Collaborators and Investigators

• Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital
• Investigators: Study Director: Suzan Şahin, Assoc.Prof., Izmir Democracy University

Publications and helpful links

General Publications

• Hung TH, Hsieh TT. Pregestational body mass index, gestational weight gain, and risks for adverse pregnancy outcomes among Taiwanese women: A retrospective cohort study. Taiwan J Obstet Gynecol. 2016 Aug;55(4):575-81. doi: 10.1016/j.tjog.2016.06.016.
• Zhao R, Xu L, Wu ML, Huang SH, Cao XJ. Maternal pre-pregnancy body mass index, gestational weight gain influence birth weight. Women Birth. 2018 Feb;31(1):e20-e25. doi: 10.1016/j.wombi.2017.06.003. Epub 2017 Jul 14.
• Heslehurst N, Ells LJ, Simpson H, Batterham A, Wilkinson J, Summerbell CD. Trends in maternal obesity incidence rates, demographic predictors, and health inequalities in 36,821 women over a 15-year period. BJOG. 2007 Feb;114(2):187-94. doi: 10.1111/j.1471-0528.2006.01180.x.

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2022
• Primary Completion (Actual): February 28, 2023
• Study Completion (Actual): June 15, 2024

Study Registration Dates

• First Submitted: July 27, 2024
• First Submitted That Met QC Criteria: August 1, 2024
• First Posted (Actual): August 6, 2024

Study Record Updates

• Last Update Posted (Actual): August 6, 2024
• Last Update Submitted That Met QC Criteria: August 1, 2024
• Last Verified: August 1, 2024

More Information

Terms related to this study

• Keywords: Syrian; immigrant; Maternal obesity; Turkish; neonatal outcome; weight gain in pregnancy
• Additional Relevant MeSH Terms: Overnutrition; Nutrition Disorders; Overweight; Body Weight Changes; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Obesity; Body Weight; Birth Weight; Weight Gain; Pregnancy Complications; Obesity, Maternal; Gestational Weight Gain
• Other Study ID Numbers: BucaSeyfiDemirsoyRTH

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No