End-of-life Decision-making Among Young Patients With Advanced Cancer: a Grounded Theory Approach

The purpose of this qualitative research is to use grounded theory to explore and describe the thoughts of young advanced cancer patients regarding end-of-life care and how these thoughts influence the related decision-making process.

Study Overview

• Status: Recruiting
• Conditions: End-of-life Decision-making

• Study Type: Observational
• Enrollment (Estimated): 30

Contacts and Locations

• Study Contact: Name: Pei-Yu Hsu; Phone Number: 267940 +886-23123456; Email: 020854@ntuh.gov.tw

Study Locations

• Taiwan
  • Taipei, Taiwan, 100
    • Recruiting
    • National Taiwan University Hospital
    • Contact: Pei-Yu Hsu; Phone Number: 267940 +886-23123456; Email: 020854@ntuh.gov.tw

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

• The patient has a solid tumor.
• The age at initial cancer diagnosis is between 15 and 39 years.
• The patient is at least 18 years old at the time of enrollment.
• The patient has cancer with metastasis, either present at initial diagnosis or occurring after treatment or follow-up.
• After metastasis, the first-line curative treatment is ineffective.

Description

Inclusion Criteria:

• The patient has a solid tumor.
• The age at initial cancer diagnosis is between 15 and 39 years.
• The patient is at least 18 years old at the time of enrollment.
• The patient has cancer with metastasis, either present at initial diagnosis or occurring after treatment or follow-up.
• After metastasis, the first-line curative treatment is ineffective.

Exclusion Criteria:

- Patients who, for any reason, including severe psychological distress (as determined by the attending physician, psychiatrist, or specialist nurse based on assessments and impressions during routine patient care), cognitive impairment, or physical limitations (such as frailty), are unable to communicate or participate in an interview lasting more than 30 minutes.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Young Patients With Advanced Cancer; The patient has a solid tumor.; The age at initial cancer diagnosis is between 15 and 39 years.; The patient is at least 18 years old at the time of enrollment.; The patient has cancer with metastasis, either present at initial diagnosis or occurring after treatment or follow-up.; After metastasis, the first-line curative treatment is ineffective.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Interview Guide	1.The journey since diagnosis. 2. The most profound or recent medical decision. 3. The most profound or recent medical decision. 4. Anticipated future medical decisions. 5. Future end-of-life care options	2024/7~2025/7

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital

Study record dates

Study Major Dates

• Study Start (Actual): July 23, 2024
• Primary Completion (Estimated): July 1, 2025
• Study Completion (Estimated): July 1, 2025

Study Registration Dates

• First Submitted: August 4, 2024
• First Submitted That Met QC Criteria: August 11, 2024
• First Posted (Actual): August 13, 2024

Study Record Updates

• Last Update Posted (Actual): August 13, 2024
• Last Update Submitted That Met QC Criteria: August 11, 2024
• Last Verified: August 1, 2024

More Information

Terms related to this study

• Keywords: Advanced Cancer; Young Patients; Grounded Theory
• Additional Relevant MeSH Terms: Pathologic Processes; Death
• Other Study ID Numbers: 202406142RINE

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No