The Factors Associated 30-day Mortality After Perioperative Cardiac Arrest in Adults Undergoing Non-cardiac Surgery.

The Factors Associated 30-day Mortality After Perioperative Cardiac Arrest in Adults Undergoing Non-cardiac Surgery: A 7-year Observational Study From a Tertiary Care University Hospital

Perioperative cardiac arrest (PCA) in patients undergoing noncardiac surgery is a rare but potentially catastrophic event associated with high mortality. Several studies have highlighted the factors contributing to PCA in the surgical population. However, information on outcomes after PCA among the surgical population is still limited. Our study aims to identify the incidence of PCA, 30-days mortality and the factors associated with PCA and 30-day mortality after PCA in adults undergoing non-cardiac surgery

Study Overview

• Status: Completed
• Conditions: Cardiac Arrest; Perioperative Complication

• Study Type: Observational
• Enrollment (Actual): 105

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients >eighteen years that had non-cardiac surgery under anesthesia and a history of PCA between January 2015 and December 2021 were eligible for inclusion. Patients with a do not resuscitate (DNR) order, who did not receive cardiopulmonary resuscitation (CPR) during PCA, or with incomplete data regarding 30-day mortality were excluded. PCA was defined as the absence of mechanical heart function (determined by a central pulse) and loss of effective circulation between the administration of anesthesia until 24 hours after surgery

Description

Inclusion Criteria:

• patients aged> 18 years old
• history of perioperative cardiac arrest
• non- cardiac surgery

Exclusion Criteria:

• did not receive cardiopulmonary resuscitation (CPR) during PCA
• incomplete data regarding 30-day mortality were excluded

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
incidence of 30 days mortality after perioperative cardiac arrest	incidence of 30 days mortality after perioperative cardiac arrest	30 days

Collaborators and Investigators

• Sponsor: Siriraj Hospital

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2015
• Primary Completion (Actual): December 31, 2021
• Study Completion (Actual): December 31, 2021

Study Registration Dates

• First Submitted: November 26, 2024
• First Submitted That Met QC Criteria: November 26, 2024
• First Posted (Actual): December 2, 2024

Study Record Updates

• Last Update Posted (Estimated): December 4, 2024
• Last Update Submitted That Met QC Criteria: November 29, 2024
• Last Verified: November 1, 2024

More Information

Terms related to this study

• Keywords: Critical care; Perioperative cardiac arrest
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Heart Diseases; Heart Arrest
• Other Study ID Numbers: 321/2022

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No