Comparing Effects of Whole Body Vibration and Resisted Training on Quadriceps Strength After Lower Limb Burns

Whole Body Vibration Versus Resisted Training on Strength of Quadriceps Post Lower Limb Burn.

Evaluate the therapeutic effect of Whole body vibration and Resistance training on strength of quadriceps post lower limb burn

Study Overview

• Status: Completed
• Conditions: Muscle Weakness Condition; Lower Limb Burn
• Intervention / Treatment: Device: whole body vibration; Other: Resistance Exercise

Detailed Description

Study Design:

This randomized controlled trial will include 60 patients suffering from partial thickness burns. The patients will be randomly divided into two equal groups, with each group consisting of 30 patients.

Study Explanation:

A verbal explanation about the importance of the study, its procedures, main aims, and conceptual approach will be provided to every patient.

Study Procedures:

The procedures of this study will be divided into two main categories: evaluation procedures and treatment procedures.

Evaluation Procedures:

Evaluation will be conducted using isokinetic dynamometry for all patients both before and after the study.

Treatment Procedures:

First Group: Patients in the first group will receive whole body vibration therapy.

Second Group: Patients in the second group will undergo resisted exercises.

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt, 12613
    • Faculty of Physical Therapy Cairo University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

The subject selection will be according to the following criteria:

• Age range between 25-40 years.
• Male and female patients will participate in the study.
• All patients have burn of 30% to 40%.
• All patients have burn at lower limb
• All patients have second degree burn
• All patients have no chronic diseases.
• All patients enrolled to the study will have their informed consent

Exclusion Criteria:

The potential participants will be excluded if they meet one of the following criteria:

• Prosthesis;
• Any neurological, musculoskeletal,or other chronic disease
• Participation in an outside resistance training programs
• Recent fracture or bone injury
• Any medication that could affect strength adaptations and adversely affect the results of the study
• Previous brain injury
• Any disease affecting balance, vestibular or visual disorders
• History of epilepsy.
• Cardiac diseases.
• Burn of sole of foot.
• Exposed foot tendons.
• Severe osteopathy.
• Marked anemia (Ht<25%).
• Serious peripheral vessel disease
• Acute medical problem at study onset.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: group A; whole body vibration group	Device: whole body vibration; Standing in different static positions or exercising on a vibrating platform.The mechanical stimuli of vibration transmitted to the body and stimulate muscle spindles which activate the alpha motor neurons and initiates muscle contractions comparable to the ''tonic vibration reflex. The effect of WBV on the neuromuscular properties of skeletal muscles and spinal mechanisms is demonstrated by a decreased electromechanical delay.
Active Comparator: group B; resistance exercises	Other: Resistance Exercise; Resistance training as a mode of exercise to promote several health benefits, including improvements in the muscle mass and strength of healthy adults.Resistance training, where muscles are required to contract against an opposing load, has been shown to be a beneficial form of rehabilitation in clinical populations prone to muscle wasting, providing stimuli to increase protein synthesis and muscle mass.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Increase in quadriceps muscle strength, assessed by an isokinetic dynamometer, which measures the peak torque of the quadriceps.	8 weeks

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Study Director: Eman Mohamed Othman, doctoral degree, Cairo university; Study Chair: Khadra Mohamed Ali, Doctoral degree, Cairo university; Study Director: Ashraf El Sebaie Mohamed, doctoral, Cairo university

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2023
• Primary Completion (Actual): July 1, 2024
• Study Completion (Actual): August 1, 2024

Study Registration Dates

• First Submitted: January 20, 2025
• First Submitted That Met QC Criteria: January 24, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: January 24, 2025
• Last Verified: January 1, 2025

More Information

Terms related to this study

• Keywords: Isokinetic; Burn; Whole Body Vibration; Resisted Exercise
• Additional Relevant MeSH Terms: Neurologic Manifestations; Musculoskeletal Diseases; Nervous System Diseases; Muscular Diseases; Neuromuscular Manifestations; Wounds and Injuries; Pathologic Processes; Muscle Weakness; Burns
• Other Study ID Numbers: P.T.REC/012/002762

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No