Prone Position Assessed by 3D EIT

Prone Position Assessment by 3D EIT in ARDS Patients

To investigate global and regional changes in lung ventilation and perfusion induced by prone position in ARDS patients assessed by 3D-EIT. And to investigate the difference between 2D-EIT and 3D-EIT in prone position monitoring.

Study Overview

• Status: Recruiting
• Conditions: Respiratory Failure; ARDS (Acute Respiratory Distress Syndrome)
• Intervention / Treatment: Behavioral: Prone position

• Study Type: Observational
• Enrollment (Estimated): 30

Contacts and Locations

• Study Contact: Name: Huaiwu He; Phone Number: 01069152301; Email: tjmuhhw@163.com

Study Locations

• China
  • Beijing Municipality
    • Beijing, Beijing Municipality, China, 100730
      • Recruiting
      • Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
      • Contact: Yun Long; Phone Number: 15201518815; Email: icu_longyun@126.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Patients with ARDS on mechanical ventilation

Description

Inclusion Criteria:

• patients on mechanical ventilation.
• Diagnosis of ARDS was based on the Berlin definition
• Patients in need of prone position because of clinical condition

Exclusion Criteria:

• Under 18 years of age.
• Pregnant women;
• Ribcage malformation
• Any contraindication to the use of EIT (e.g. automatic implantable cardioverter defibrillator, and implantable pumps).

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Regional ventilation monitored by EIT	Using EIT to monitor the regional ventilation during supine and prone position, to monitor the ventilation distribution change.	5-10minutes
Regional perfusion monitored by EIT	Using EIT to monitor the regional perfusion during supine and prone position, to monitor the ventilation distribution change.	5-10minutes
V/Q monitored by EIT	Ventilation and perfusion monitored by EIT in supine and prone position. To evaluate the V/Q match, deadspace and shunt lung region.	5-10minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Respiratory system compliance	Monitor the respiratory system compliance during supine and prone position	1 day
SpO2	Monitor the SpO2 during supine and prone position	1 day

Collaborators and Investigators

• Sponsor: Peking Union Medical College Hospital

Study record dates

Study Major Dates

• Study Start (Actual): October 31, 2024
• Primary Completion (Estimated): October 31, 2026
• Study Completion (Estimated): December 30, 2026

Study Registration Dates

• First Submitted: November 14, 2024
• First Submitted That Met QC Criteria: July 17, 2025
• First Posted (Actual): July 24, 2025

Study Record Updates

• Last Update Posted (Actual): January 26, 2026
• Last Update Submitted That Met QC Criteria: January 23, 2026
• Last Verified: January 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases; Respiration Disorders; Lung Injury; Respiratory Insufficiency; Acute Lung Injury; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Posture; Prone Position
• Other Study ID Numbers: Prone position by 3D-EIT

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No