Understanding the Long-term Paths of People With Addictions (ADDICT AQUI)

Trajectories of People With Substance or Behavioral Addictions in Contact With the Healthcare System: Medical, Neurobiological, Sociological, and Psychological Characteristics. Multicenter, Multidisciplinary Prospective Study.

The study is an open prospective cohort study. Participants are assessed at the start of their care in an addiction treatment unit using the Addiction Severity Index (ASI) and the Mini International Neuropsychiatric Interview (MINI), which are routinely conducted in these centers for individuals with substance use or behavioral disorders. After the study protocol is explained, the evaluator checks eligibility criteria, interested participants provide their written informed consent. The evaluator invites participants to complete self-administered questionnaires at home, which are returned during a session that also includes cognitive testing. Follow-up interviews are scheduled at 3 months, 6 months, and every 6 months thereafter.

Study Overview

• Status: Recruiting
• Conditions: Addiction; Addictive Behaviors; Addiction Disorders
• Intervention / Treatment: Other: Addiction Severity Index

• Study Type: Observational
• Enrollment (Estimated): 10000

Contacts and Locations

• Study Contact: Name: Marc AURIACOMBE, Prof, MD, PhD; Phone Number: +33 5 56 56 17 38; Email: marc.auriacombe@u-bordeaux.fr
• Study Contact Backup: Name: Helen SAVARIEAU; Phone Number: + 33 556563556; Email: hsavarieau@ch-perrens.fr

Study Locations

• France
  • Gironde
    • Bordeaux, Gironde, France, 33076
      • Recruiting
      • Centre Hospitalier Charles Perrens
      • Contact: Nicole DUBUCH; Phone Number: +33556563556; Email: ndubuch@ch-perrens.fr
      • Contact: helen SAVARIEAU; Phone Number: +33 556563556; Email: hsavarieau@ch-perrens.fr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Healthcare units : CSAPA de Bordeaux and CSAPA de Bayonne.

Description

Inclusion Criteria:

• Seeking treatment for substance or behavioral addiction at one of the inclusion centers, with more than one month to wait before treatment begins
• Presenting with at least one substance or behavioral addiction (according to DSM5 criteria)

Exclusion Criteria:

• Condition incompatible with understanding assessment tools
• Difficulties understanding and/or writing French
• Person unable to give personal consent

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Usual care	Other: Addiction Severity Index; Once recruited, self-questionnaires completed by the participant at home and brought back at next visite, during which the participant takes cognitive tests. Follow-up interviews are scheduled at 3 months, 6 months, and then every 6 months.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Severity of addiction	ASI composite score	at Day 0, at Month 3, at Month 6 and at each following 6-month visit

Collaborators and Investigators

• Sponsor: Centre Hospitalier Charles Perrens, Bordeaux
• Investigators: Principal Investigator: Marc AURIACOMBE, Prof Md PhD, CH. Charles Perrens

Publications and helpful links

General Publications

• Petry NM, Blanco C, Auriacombe M, Borges G, Bucholz K, Crowley TJ, Grant BF, Hasin DS, O'Brien C. An overview of and rationale for changes proposed for pathological gambling in DSM-5. J Gambl Stud. 2014 Jun;30(2):493-502. doi: 10.1007/s10899-013-9370-0.
• Hasin DS, O'Brien CP, Auriacombe M, Borges G, Bucholz K, Budney A, Compton WM, Crowley T, Ling W, Petry NM, Schuckit M, Grant BF. DSM-5 criteria for substance use disorders: recommendations and rationale. Am J Psychiatry. 2013 Aug;170(8):834-51. doi: 10.1176/appi.ajp.2013.12060782.
• O'Brien C. Addiction and dependence in DSM-V. Addiction. 2011 May;106(5):866-7. doi: 10.1111/j.1360-0443.2010.03144.x. Epub 2010 Oct 6.

Study record dates

Study Major Dates

• Study Start (Actual): March 12, 2002
• Primary Completion (Estimated): December 31, 2030
• Study Completion (Estimated): December 31, 2035

Study Registration Dates

• First Submitted: September 29, 2025
• First Submitted That Met QC Criteria: November 24, 2025
• First Posted (Actual): November 25, 2025

Study Record Updates

• Last Update Posted (Actual): November 25, 2025
• Last Update Submitted That Met QC Criteria: November 24, 2025
• Last Verified: November 1, 2025

More Information

Terms related to this study

• Keywords: addictive behavior; Addiction; addiction disorders
• Additional Relevant MeSH Terms: Compulsive Behavior; Impulsive Behavior; Behavior; Behavior, Addictive
• Other Study ID Numbers: 01-20 ADDICTAQUI; CCPPRB BORDEAUX B (Other Identifier: Ethic Committee)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No