Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation

January 20, 2026 updated by: Bonnie Halpern-Felsher, Stanford University

Evaluation of the Smart Talk: Cannabis Awareness and Prevention Curriculum

The Stanford REACH Lab's SMART TALK: Cannabis Awareness and Prevention Toolkit is a free, online educational resource to be used by educators to increase knowledge and awareness of cannabis and reduce use among youth. The aim of this study is to investigate the extent to which the curriculum changes middle and high school students' intentions to use and actual use of cannabis.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Smart Talk includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at addressing key factors associated with youth cannabis use, including changing adolescents' attitudes towards and misperceptions about cannabis; increasing their refusal skills to pulls of marketing and social media; reducing stress and depression which have been linked to cannabis initiation and use; improving coping skills; and decreasing intentions and actual use of all cannabis products.

Study Type

Interventional

Enrollment (Estimated)

10800

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • California
      • Palo Alto, California, United States, 94304
        • Stanford University
        • Principal Investigator:
          • Bonnie Halpern Felsher, Ph.D.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Middle school and high school students receiving health education at schools participating in the study

Exclusion Criteria:

-

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Smart Talk Cannabis Awareness and Prevention
At the start of Year 2, schools will be randomized in a 1:1 ratio to either receive 'Stanford REACH Lab's Smart Talk: Cannabis Prevention and Awareness' curriculum or 'delay-in-treatment (standard of care)'. Students in these schools will receive the Stanford curriculum designed as a 5-session course administered in a school class-room setting.
Behavioral: Behavioral: Smart Talk Cannabis Awareness and Prevention
Behavioral:Smart Talk includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at addressing key factors associated with youth cannabis use, including changing adolescents' attitudes towards and misperceptions about cannabis; increasing their refusal skills to pulls of marketing and social media; reducing stress and depression which have been linked to cannabis initiation and use; improving coping skills; and decreasing intentions and actual use of all cannabis products.
Experimental: Delay in Treatment Group
At the start of Year 2, schools randomized to the delay-in-treatment group will receive a standard of care for one year. After year 2, the delay-in-treatment group will crossover to receive 'Stanford REACH Lab's Healthy Futures: Cannabis Prevention and Awareness until year 5 (receive intervention for years 2 to 4).
Behavioral: Behavioral: Smart Talk Cannabis Awareness and Prevention
Behavioral:Smart Talk includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at addressing key factors associated with youth cannabis use, including changing adolescents' attitudes towards and misperceptions about cannabis; increasing their refusal skills to pulls of marketing and social media; reducing stress and depression which have been linked to cannabis initiation and use; improving coping skills; and decreasing intentions and actual use of all cannabis products.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in cannabis use
Time Frame: Baseline to follow-up at approximately 182 weeks
Investigator-originated survey measures (questions) assess ever cannabis use & past 30-day cannabis use. This outcome measure assesses cannabis use.
Baseline to follow-up at approximately 182 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in intention to use cannabis in the future
Time Frame: Baseline to follow-up at approximately 182 weeks
Investigator-originated survey measures (questions) assessing change in participant intention to use cannabis in the future
Baseline to follow-up at approximately 182 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Stanford University

Collaborators

National Institute on Drug Abuse (NIDA)

Investigators

  • Principal Investigator: Bonnie Halpern Felsher, Ph.D., Stanford University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

September 1, 2029

Study Completion (Estimated)

February 1, 2030

Study Registration Dates

First Submitted

January 20, 2026

First Submitted That Met QC Criteria

January 20, 2026

First Posted (Actual)

January 22, 2026

Study Record Updates

Last Update Posted (Actual)

January 22, 2026

Last Update Submitted That Met QC Criteria

January 20, 2026

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 80402
  • 1R01DA060900-01A1 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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