Comparative Effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in Patients With Total Knee Replacement.

January 15, 2026 updated by: Kainat Zahara, Rashid Latif Medical College
Comparative effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in patients with Total Knee Replacement

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Total knee replacement (TKR) is an elective procedure in which the knee joint is resurfaced with a metal or plastic implant intended to restore function, provide pain relief, and improve quality of life.IASTM helps to remove the scarring and decrease the pain caused by muscular tightness. The therapeutic benefits of the application of IASTM occur in a short period, including improvement in range of motion, reduction of pain, decreasing hypertonia.Cross fiber massage, is a form of massage technique that focuses on the body's deep tissues. The massage is deep and should be delivered in transverse direction to the particular tissue affected, as opposed to superficial massage applied longitudinally parallel to the vessels, which promotes circulation and fluid return.

Study Type

Interventional

Enrollment (Actual)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
    • Punjab Province
      • Lahore, Punjab Province, Pakistan, 54000
        • Arif Memorial Teaching Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Both male and female of Age 40-60
  • Radiological diagnosis
  • Advanced degenerative OA knee, undergoing a primary TKR
  • Pain intensity >3

Exclusion Criteria:

  • Rheumatoid Arthritis patients
  • Septic Arthritis and other inflammatory arthritis patients
  • Secondary or traumatic O.A
  • Congenital bony deformities
  • Flexion contracture, patellar dislocation
  • Fracture or pervious osteotomy
  • Neurological dysfunction

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Instrument Assisted Soft Tissue Mobilization
The Graston Technique of Soft-Tissue Therapy (GT), also known as instrument-assisted soft tissue mobilization (IASTM), is used by chiropractors, physicians, and therapists to manage pain and range-of-motion limitations caused by scar tissue and musculoskeletal injuries. The GT treats tissue injuries and pain by separating scar tissue and producing heat, which increases blood flow to the areas affected by pain or trauma.
Other: Instrument-assisted soft tissue mobilization
Each treatment session was of 15-20 minutes for all muscles, with the help of IASTM device assisted by friction-free oil or gel. The general principle is a six-step technique comprising examination, warm-up, IASTM, stretching, strengthening and icing. Data was collected by an independent assessor at baseline and after 4 weeks
Active Comparator: Cross Fibre Massage
Deep tissue massage is a type of massage that focuses on the muscular tissue's most profound levels. In tight regions, therapists utilize a combination of gentle strokes and deep pressure with their fingers, palms, and forearms. Either following or by going over the muscle fibers. It is used for back pain Reduce high blood pressure, Relieve pain and stiffness Speed up the healing of muscle strains and sprains Chronic constipation.
Other: Cross Fibre Massage

The massage is deep and must be applied transversely to the specific tissue involved unlike the superficial massage given in the longitudinal direction parallel to the vessels which enhances circulation and return of fluid. The therapist's fingers and patient's skin must move as one, otherwise moving subcutaneous fascia against muscle or ligament could lead to blister formation or subcutaneous bruising.

Data was collected by an independent assessor at baseline and after 4 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pain Intensity
Time Frame: Baseline and 4th week
Visual Analogue Scale (VAS) is a widely used tool to measure pain intensity. The visual analog scale (VAS) for pain is a straight line with one end meaning no pain and the other end meaning the worst pain imaginable. It was used to assess pain.
Baseline and 4th week

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Range Of Motion
Time Frame: Baseline and 4th week
An inclinometer app is a tool that helps measure and track changes in joint mobility, flexibility, and range of motion. It provide objective, reliable degree measurements of knee range of motion and joint position sense error. These measurements are then compared against established normal ranges or the patient's own previous results to track progress.
Baseline and 4th week

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Knee Funtion
Time Frame: Baseline and 4th week
The Knee Injury and Osteoarthritis Outcome Score (KOOS) is a self-reported outcome measure assessing the patient's opinion about the health, symptoms, and functionality of their knee. It is a questionnaire, including 5 subscales: symptoms, pain, ADLs, sports/recreation, and quality of life.
Baseline and 4th week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Rashid Latif Medical College

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 15, 2024

Primary Completion (Actual)

December 25, 2024

Study Completion (Actual)

January 8, 2026

Study Registration Dates

First Submitted

January 15, 2026

First Submitted That Met QC Criteria

January 15, 2026

First Posted (Actual)

January 23, 2026

Study Record Updates

Last Update Posted (Actual)

January 23, 2026

Last Update Submitted That Met QC Criteria

January 15, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IRB/2024/168

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

The data will be available on reasonable request from corresponding author.

IPD Sharing Time Frame

It will available after publication of study.

IPD Sharing Access Criteria

The researchers and other scientists , but after publication.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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