Improvement of Sleep Disorders in Patients With Alzheimer's Disease After Sunlight Exposure Therapy.

February 2, 2026 updated by: National Taiwan University Hospital

An Analysis of the Improvement of Sleep Disorders in Patients With Alzheimer's Disease After Sunlight Exposure Therapy.

This observational study aimed to understand the effect of intervention A on sleep disorders in individuals with Alzheimer's disease receiving sunlight therapy. The primary question of the study was:

Does sunlight therapy improve sleep disorders in Alzheimer's disease?

Participants will complete a questionnaire, undergo sunlight therapy, and have their sleep patterns recorded for 14 days.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
    • Taiwan
      • Taipei, Taiwan, Taiwan, 100
        • National Taiwan University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Diagnosed with Alzheimer's disease
  2. CDR: 0.5 - 1 point
  3. Conscious and able to cooperate with behavioral interventions and telephone interviews
  4. Complaints of sleep disturbances, including: daytime sleepiness, difficulty falling asleep, fragmented sleep, nighttime awakening, nocturnal wandering, and sunset syndrome.
  5. A cohabiting family member is required as the primary caregiver, who understands and cooperates with this intervention and has signed a consent form.
  6. If the patient is already taking sleeping pills, the maintenance dose will not be adjusted.

Exclusion Criteria:

  1. Individuals with other brain injury conditions, such as cerebral palsy, brain tumors, traumatic brain injury, or stroke.
  2. Individuals with visual impairments (assessed by comparing numbers with fingers at a distance of 30 cm upon admission).
  3. Institutional residents.
  4. Individuals living alone.
  5. Individuals unable to cooperate with behavioral interventions and telephone interviews.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: N/A
  • Interventional Model: Sequential Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Routine nursing care
no additional sunlight therapy
Behavioral: sunlight therapy
They were informed that sun exposure therapy could effectively improve sleep, and behavioral interventions were discussed to develop a health education plan. Telephone follow-ups were conducted on days 3, 7, 10, and 14 after enrollment to understand the sun exposure practices of the experimental group, including the duration of sun exposure, whether the light source was indoor light or sunlight, and positive encouragement was provided.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pittsburgh Sleep Quality Index, PSQI
Time Frame: on enrollment days, 7, and 14 after enrollment
The Pittsburgh Sleep Quality Index (PSQI) assesses sleep quality. It has seven dimensions: sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbance, medication use, and daytime activity impairment. A higher PSQI score indicates poorer sleep quality. The total score ranges from 0 to 21, with a minimum score of 0, indicating very good sleep quality over the past month. Lower scores indicate better sleep quality, while a total score of 5 or below is generally considered to indicate fair sleep quality.
on enrollment days, 7, and 14 after enrollment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 9, 2026

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

January 15, 2026

First Submitted That Met QC Criteria

February 2, 2026

First Posted (Actual)

February 4, 2026

Study Record Updates

Last Update Posted (Actual)

February 4, 2026

Last Update Submitted That Met QC Criteria

February 2, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 202511021RIND

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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