Effects of Thoracolumbar Stabilization Versus Spinal Decompression Exercises on Maigne's Syndrome

Comparative Effects of Thoracolumbar Stabilization Exercises Versus Spinal Decompression Exercises on Pain, Range of Motion, Disability and Posture in Patients With Maigne's Syndrome.

The study was conducted to compare the effect of thoracolumbar stabilization exercises versus spinal decompression exercises on pain, range of motion, disability and posture in patients with maigne's syndrome.

Study Overview

• Status: Completed
• Conditions: Syndrome, Manganese Neurotoxicity
• Intervention / Treatment: Other: Lumbothoracic stabilization exercises; Other: Standardized physical therapy treatment; Other: Spinal decompression exercises

• Study Type: Interventional
• Enrollment (Actual): 26
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab Province
    • Lahore, Punjab Province, Pakistan, 5400
      • Bahria nasheman medical center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Age 20-45, Male/ Female NPRS > 4 Pain at T12-L1 and ipsilateral gluteal and/or groin pain. Local Tenderness on palpation at TLJ Sharp pain on palpation at posterior iliac crest • Positive KIBLER Skin fold Test on affected side. Allodynia or Hyperalgesia observed at sensory testing (pinprick and light touch) on ipsilateral side Negative Radiological Imaging for any bony deformity

Exclusion Criteria:

• Any structural abnormalities like fractures/spondylosis History of any neurological or musculoskeletal problems History of cervical or thoracic surgery Psychological disorders. Cauda equina syndrome History of abdominal or groin pain Patients with positive FABER test, SLR test, Hip score test and SIJ compression test (30) Patients with positive Slump test, QL tightness, FAIR test

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Thoracolumbar stabilization exercises	Other: Lumbothoracic stabilization exercises; Each exercise session was performed for 30 minutes, with 3 sessions per week.; st Week, Isolated contraction of transverse abdominis and lumbar multifidus training was performed with 2 sets of 10 repetition, 10 second hold each time and rest period of 5 min.; nd week, co-contraction of transverse abdominis and multifidus in sitting and lying position was performed with 2 sets of 10 repetition, 10 second hold each time and rest period of 5 min.; rd week, co-contraction of transverse abdominis and multifidus in quadruped and standing position was performed with 2 sets of 10 repetition, 10 second hold each time and rest period of 5 min.; Other: Standardized physical therapy treatment; Electric hot pack for 7 minutes. TENS 120 Hz at low intensity and 50-200μs pulse duration with electrodes placed in a crisscross pattern at T9 - L1 for 10 min Grade I & II Maitland posteroanterior central (PAC) glide and unilateral posterior anterior glide (UPA) in 3 sets of 1 minute each with 1 minute interval at T9-L2
Active Comparator: Spinal decompression exercises	Other: Standardized physical therapy treatment; Electric hot pack for 7 minutes. TENS 120 Hz at low intensity and 50-200μs pulse duration with electrodes placed in a crisscross pattern at T9 - L1 for 10 min Grade I & II Maitland posteroanterior central (PAC) glide and unilateral posterior anterior glide (UPA) in 3 sets of 1 minute each with 1 minute interval at T9-L2; Other: Spinal decompression exercises; The exercise session was performed for 30 minutes, with 3 sessions per week In 1st week , patient performed pelvic tilt (lying), cat-cow stretch, thoracic extension on folded towel, child pose and plank . Each exercise was performed with 3 sets of 12 reps with 5-6 sec hold, with a rest of 30 sec In 2nd week, patient performed pelvic tilt (sitting) , cat cow stretch, thoracic extension on foam roller, child pose with side stretch and plank. . Each exercise was performed with 3 sets of 12 reps with 5-6 sec hold, with a rest of 30 sec. In 3rd week, patient performed pelvic tilt ( standing ), cat cow stretch, thoracic extension on gym ball, child pose with passive stretch and side plank. . Each exercise was performed with 3 sets of 12 reps with 5-6 sec hold, with a rest of 30 sec.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Revised Oswestry Low Back Pain Disability Questionnaire	The Revised Oswestry Low Back Pain Disability Questionnaire (ODI) is a commonly used self-reported measure consisting of 10 sections that evaluate the impact of low back pain on everyday activities. It assesses areas such as pain severity, personal care, lifting, walking, sitting, standing, sleep, social activities, travel, and sexual function. The resulting score reflects the level of disability from minimal to severe and helps guide management of individuals with low back pain. In the current study it is used to measure the disability caused by thoracolumbar syndrome (Maigne's syndrome)	From enrollment to the end of 3 week treatment
Numeric pain rating scale	Numeric pain rating scale is used to evaluate pain. It consists of 11 points, having an overall score ranging from 0 and 10, where 0 represents no pain, 1-3 represents mild pain, 4-6 represents moderate pain and 7-10 represents severe pain.	From enrollment to the end of 3 week treatment

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thoracolumbar extension	Changes in thoracolumbar extension ROM at baseline and 3rd week of intervention were measured using bubble inclinometer	From enrollment to the end of 3 week treatment
Thoracolumbar rotation	Changes in thoracolumbar rotation ROM at baseline and 3rd week of intervention were measured using bubble inclinometer	From enrollment to the end of 3 week treatment
Thoracic Cobb's angle	Thoracic Cobb's angle at the baseline and 3rd week of intervention were measured using standing thoracolumbar x-ray	From enrollment to the end of 3 week treatment
Lumbar Cobb's angle	Lumbar Cobb's angle at the baseline and 3rd week of intervention were measured using standing thoracolumbar x-ray	From enrollment to the end of 3 week treatment

Collaborators and Investigators

• Sponsor: Riphah International University
• Investigators: Principal Investigator: Naila Kanwal, Riphah International University

Publications and helpful links

General Publications

• DiMond MEJJocm. Rehabilitative principles in the management of thoracolumbar syndrome: a case report. 2017;16(4):331-9.
• Fisher LR, Alvar BA, Maher SF, Cleland JAJJoo, therapy sp. Short-term effects of thoracic spine thrust manipulation, exercise, and education in individuals with low back pain: a randomized controlled trial. 2020;50(1):24-32.
• Maatman RC, Boelens OB, Scheltinga MR, Roumen RMJJoPR. Chronic localized back pain due to entrapment of cutaneous branches of posterior rami of the thoracic nerves (POCNES): a case series on diagnosis and management. 2019:715-23
• Gaowgzeh RAM, Chevidikunnan MF, BinMulayh EA, Khan FJJob, rehabilitation m. Effect of spinal decompression therapy and core stabilization exercises in management of lumbar disc prolapse: A single blind randomized controlled trial. 2020;33(2):225-31.
• Ségui Y, Ramírez-Moreno JJJoB, Therapies M. Global physiotherapy approach to thoracolumbar junction syndrome. A case report. 2021;25:6-15.
• Singh T, Kumar PJBoFoPT. Pelvic pain in Maigne's syndrome-a multi-segmental approach. 2022;27(1):4.
• Lee H, Chae H, Ryu M, Yang C, Kim SJM. Acupuncture for patients with Maigne's syndrome: A case series. 2023;102(23):e33999.
• Riaz V, Qamar S. Effects of Thoracic Extension versus Thoracic Stabilization Exercises on Pain, Stiffness, Range of Motion, Disability and Posture in patients with Maigne's Thoracic Pain
• Alptekin K, Örnek NI, Aydın T, Alkan M, Toprak M, Balcı LA, et al. Effectiveness of exercise and local steroid injections for the thoracolumbar junction syndrome (The Maigne's syndrome) treatment. 2017;11:467

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2025
• Primary Completion (Actual): May 31, 2025
• Study Completion (Actual): October 31, 2025

Study Registration Dates

• First Submitted: February 17, 2026
• First Submitted That Met QC Criteria: February 17, 2026
• First Posted (Actual): February 23, 2026

Study Record Updates

• Last Update Posted (Actual): February 23, 2026
• Last Update Submitted That Met QC Criteria: February 17, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Keywords: Traction; Core stability; Decompression; Lumbosacral plexus; Thoracic vertebrae; Lumbar vertebrae
• Additional Relevant MeSH Terms: Heavy Metal Poisoning; Nervous System Diseases; Chemically-Induced Disorders; Poisoning; Neurotoxicity Syndromes; Heavy Metal Poisoning, Nervous System; Manganese Poisoning
• Other Study ID Numbers: REC/RCR&AHS/24/0192

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No