Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease

May 31, 2026 updated by: Büşra Seçkinoğulları Korkusuz, Ankara University

Effects of Dual-Task Training on Upper Extremity Function and Muscle Thickness in Parkinson's Disease

The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are:

Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography?

Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco

Participants will:

complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

38

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
  • Modified Hoehn and Yahr stage 2 to 3
  • No medication or dosage change within the last 6 months
  • Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21
  • Voluntary participation with written informed consent

Exclusion Criteria:

  • Atypical or secondary parkinsonism
  • Advanced orthopedic condition affecting the upper extremity
  • Surgery, trauma, or immobilization involving the upper extremity within the last 6 months
  • Wound or dermatological condition preventing upper extremity ultrasonographic evaluation
  • Severe visual or hearing loss
  • Severe depression, psychosis, or communication difficulty
  • Any additional health problem preventing regular participation in the study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Dual-Task Training Group
Participants will receive dual-task training in addition to their routine daily activities. The training program will be performed 3 times per week for 8 weeks, with each session lasting 60 minutes and consisting of combined motor and cognitive tasks.
Behavioral: Dual-Task Training
Dual-task training will be applied 3 times per week for 8 weeks, with each session lasting 60 minutes. The program combines motor tasks (such as peg placement, object manipulation, bilateral coordination, and mobility tasks) with simultaneous cognitive tasks (such as backward counting, category-based word generation, and memory tasks).
No Intervention: Control Group
Participants will continue their routine daily activities without receiving any additional exercise, training, or rehabilitation intervention during the study period.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Upper Extremity Function
Time Frame: Baseline and 8 weeks
Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity.
Baseline and 8 weeks
Upper Extremity Muscle Thickness
Time Frame: Baseline and 8 weeks
Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters.
Baseline and 8 weeks
Hand Grip Strength
Time Frame: Baseline and 8 weeks
Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded.
Baseline and 8 weeks
Pinch Strength
Time Frame: Baseline and 8 weeks
Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons.
Baseline and 8 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara University

Collaborators

Hacettepe University

Investigators

  • Study Chair: Ayşenur Özcan, Çankırı Karatekin University
  • Principal Investigator: Büşra Seçkinoğulları Korkusuz, Ankara University
  • Study Chair: Süleyman Korkusuz, Atılım University
  • Study Chair: Ayla Fil, Hacettepe University
  • Study Chair: Gül Yalçın Çakmaklı, Hacettepe University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 24, 2026

Primary Completion (Estimated)

July 24, 2026

Study Completion (Estimated)

August 1, 2026

Study Registration Dates

First Submitted

April 11, 2026

First Submitted That Met QC Criteria

April 11, 2026

First Posted (Actual)

April 17, 2026

Study Record Updates

Last Update Posted (Actual)

June 2, 2026

Last Update Submitted That Met QC Criteria

May 31, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • f57111e3114a4f65

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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