Marginal Bone Level Around Dental Implants in Periodontitis Patients ((MBL))

May 20, 2026 updated by: Howida Sabry

Evaluation of Marginal Bone Level Around Dental Implants With Two Types of Surface Characteristics in Periodontitis Patients

This study evaluates and compares marginal bone level changes around dental implants with two different surface characteristics in patients with a history of periodontitis. Participants will receive dental implants and will be followed up for one year to assess bone level changes around the implants.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Patients with treated periodontitis who require dental implants will be divided into two groups based on implant surface type. Marginal bone level will be assessed radiographically at baseline, then at 3 months,6 months, and 12 months after implant placement. The study aims to determine whether implant surface characteristics influence marginal bone loss in periodontitis-susceptible patients over a one-year follow-up period.

Study Type

Interventional

Enrollment (Actual)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt
        • Faculty of Dental Medicine for Girls, Al-Azhar University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

1 - Age ranged from 35 to 55 years old, with a history of periodontitis. 2. Presence of at least one edentulous space

3. Presence of adequate bone volume to place implants and achieves primary implant stability without the need for bone reconstructive approaches. 4. Absence of systemic diseases

Exclusion Criteria:

  • 1-Presence of para-functional habits. 2-Chronic smokers or former smokers. 3-Pregnancy and lactation. 4-In addition to any patient who is not willing to follow our treatment protocol.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Factorial Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Group I - Periodontitis SLA
15 periodontitis patients receiving SLA surface implants
Device: SLA Dental Implant
Sandblasted large-grit corundum and acid-etched (SLA) surface dental implant
Experimental: Group II - Periodontitis Plasma
15 periodontitis patients receiving plasma spraying surface treated implants
Device: Plasma Spraying Dental Implant
Plasma spraying surface treated dental implant
Active Comparator: Group III - Healthy SLA
5 periodontally healthy patients receiving SLA surface implants
Device: SLA Dental Implant
Sandblasted large-grit corundum and acid-etched (SLA) surface dental implant
Active Comparator: Group IV - Healthy Plasma
5 periodontally healthy patients receiving plasma spraying surface treated implants
Device: Plasma Spraying Dental Implant
Plasma spraying surface treated dental implant

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Marginal Bone Level
Time Frame: Baseline, 3 months, 6 months, and 12 months after implant placement
Radiographic assessment of marginal bone level changes around dental implants measured in millimeters using Cone Beam Computed Tomography (CBCT)
Baseline, 3 months, 6 months, and 12 months after implant placement

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Probing Depth
Time Frame: Baseline, 3 months, 6 months, and 12 months
probing depth measured in millimeters around implants
Baseline, 3 months, 6 months, and 12 months
Gingival Index
Time Frame: Baseline, 3 months, 6 months, and 12 months
Assessment of gingival inflammation around dental implants
Baseline, 3 months, 6 months, and 12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Howida Sabry

Investigators

  • Principal Investigator: Osama Sayed EL-Shall, Professor, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Study Director: Lobna Mohamed Abd-ELaziz, Associate Professor, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 30, 2023

Primary Completion (Actual)

April 30, 2025

Study Completion (Actual)

April 30, 2026

Study Registration Dates

First Submitted

May 20, 2026

First Submitted That Met QC Criteria

May 20, 2026

First Posted (Actual)

May 27, 2026

Study Record Updates

Last Update Posted (Actual)

May 27, 2026

Last Update Submitted That Met QC Criteria

May 20, 2026

Last Verified

April 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AZHAR-OMPDR_103_2i-2023

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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