- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07670208
Physical Activity Promoting Active Aging
Physical Activity Promoting Active Aging: An Exploration of Intrinsic Mechanisms and Practical Pathways
This project aims to explore the effects and underlying mechanisms of physical activity in promoting active aging among older adults. The researchers conducted two rounds of progressive randomized controlled intervention trials to verify the effects and mechanisms of a multimodal physical activity intervention on active aging from two dimensions: intervention structure and participation mode.
In Study 1, with a 12-week intervention period, participants were randomly assigned to three groups: a Tai Chi exercise group, a multimodal exercise group, and a daily activity control group. By comparing between-group differences, the study evaluated the effects of different exercise modalities on physical function and subjective active aging.
In Study 2, also with a 12-week intervention period, participants were randomly assigned to two multimodal exercise groups differing in participation mode: an in-person group-based format versus an online individual format. This study examined the moderating effects of different participation modes on both objective and subjective active aging outcomes, while keeping the multimodal physical activity intervention content identical.
Study Overview
Status
Conditions
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
Zhejiang
-
Hangzhou, Zhejiang, China, 310058
- Department of Sports Science, College of Education, Zhejiang University
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Aged 60 years or above;
Capable of engaging in regular physical activities and comprehending basic testing procedures and instructions.
Exclusion Criteria:
- Severe cardiac, pulmonary, or musculoskeletal disorders;
History of neurological or psychiatric conditions that may impair cognitive function (e.g., stroke, Parkinson's disease, Alzheimer's disease, major depressive disorder, etc.);
Missing three or more scheduled intervention sessions during the study period, or requesting discontinuation of participation.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
No Intervention: Control group
|
|
|
Experimental: Multicomponent exercise group
|
Tai Chi, Baduanjin, strength, balance, and flexibility exercises
|
|
Experimental: Mind-body exercise group
|
Tai Chi, Yoga, and Baduanjin
|
|
Experimental: Online-based multicomponent exercise group
|
Tai Chi, Baduanjin, and strength, balance, and flexibility exercises (delivered via live online streaming and video watching)
|
|
Experimental: In-person multicomponent exercise group
|
Tai Chi, Baduanjin, and strength, balance, and flexibility exercises (delivered in an in-person group format)
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Active aging
Time Frame: week0, week6, week12
|
It was measured using the Active Aging Questionnaire.
|
week0, week6, week12
|
|
General self-efficacy
Time Frame: week0, week6, week12
|
It was measured using the General Self-Efficacy Scale.
|
week0, week6, week12
|
|
Cognitive function
Time Frame: week0, week6, week12
|
Cognitive function was measured using the cognitive subscale of the LEIPAD questionnaire
|
week0, week6, week12
|
|
Cognitive function assessed by the Montreal Cognitive Assessment (MOCA)
Time Frame: week0, week6, week12
|
Cognitive function was measured using the Montreal Cognitive Assessment (MOCA).
|
week0, week6, week12
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Height
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
Weight
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
Body fat percentage
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
Vital capacity test
Time Frame: week0, week6, week12
|
Physiological parameter
|
week0, week6, week12
|
|
2-minute high-knee marching in place
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
Handgrip strength
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
Sit and reach test
Time Frame: week0, week6, week12
|
week0, week6, week12
|
|
|
30-second chair stand test
Time Frame: week0, week6, week12
|
Physiological parameter
|
week0, week6, week12
|
|
One-legged stance with eyes closed tesr
Time Frame: week0, week6, week12
|
Physiological parameter
|
week0, week6, week12
|
|
Choice reaction time
Time Frame: week0, week6, week12
|
week0, week6, week12
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- ZJU-SSEC/2025/No.6
- 23NDJC001Z (Other Grant/Funding Number: Key Program of Philosophy and Social Sciences Planning of Zhejiang Province)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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